Global to push GA events into
skip to main content

Title: Producing dicarboxylic acids using polyketide synthases

The present invention provides for a polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid). Such diacids include diketide-diacids and triketide-diacids. The invention includes recombinant nucleic acid encoding the PKS, and host cells comprising the PKS. The invention also includes methods for producing the diacids.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1182574
Assignee:
The Regents of the University of California (Oakland, CA) CHO
Patent Number(s):
9,040,282
Application Number:
14/038,488
Contract Number:
AC02-05CH11231
Research Org:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Other works cited in this record:

Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units
journal, February 2001

Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway
journal, June 2007
  • Erb, T. J.; Berg, I. A.; Brecht, V.
  • Proceedings of the National Academy of Sciences, Vol. 104, Issue 25, p. 10631-10636
  • DOI: 10.1073/pnas.0702791104

Similar records in DOepatents and OSTI.GOV collections: