Multi-modality nanoparticles having optically responsive shape
Abstract
In certain embodiments novel nanoparticles (nanowontons) are provided that are suitable for multimodal imaging and/or therapy. In one embodiment, the nanoparticles include a first biocompatible (e.g., gold) layer, an inner core layer (e.g., a non-biocompatible material), and a biocompatible (e.g., gold) layer. The first gold layer includes a concave surface that forms a first outer surface of the layered nanoparticle. The second gold layer includes a convex surface that forms a second outer surface of the layered nanoparticle. The first and second gold layers encapsulate the inner core material layer. Methods of fabricating such nanoparticles are also provided.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1179791
- Patent Number(s):
- 9037214
- Application Number:
- 13/202,976
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
B - PERFORMING OPERATIONS B22 - CASTING B22F - WORKING METALLIC POWDER
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2010 Feb 23
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 77 NANOSCIENCE AND NANOTECHNOLOGY; 60 APPLIED LIFE SCIENCES; 36 MATERIALS SCIENCE
Citation Formats
Chen, Fanqing, and Bouchard, Louis-Serge. Multi-modality nanoparticles having optically responsive shape. United States: N. p., 2015.
Web.
Chen, Fanqing, & Bouchard, Louis-Serge. Multi-modality nanoparticles having optically responsive shape. United States.
Chen, Fanqing, and Bouchard, Louis-Serge. Tue .
"Multi-modality nanoparticles having optically responsive shape". United States. https://www.osti.gov/servlets/purl/1179791.
@article{osti_1179791,
title = {Multi-modality nanoparticles having optically responsive shape},
author = {Chen, Fanqing and Bouchard, Louis-Serge},
abstractNote = {In certain embodiments novel nanoparticles (nanowontons) are provided that are suitable for multimodal imaging and/or therapy. In one embodiment, the nanoparticles include a first biocompatible (e.g., gold) layer, an inner core layer (e.g., a non-biocompatible material), and a biocompatible (e.g., gold) layer. The first gold layer includes a concave surface that forms a first outer surface of the layered nanoparticle. The second gold layer includes a convex surface that forms a second outer surface of the layered nanoparticle. The first and second gold layers encapsulate the inner core material layer. Methods of fabricating such nanoparticles are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {5}
}
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