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Title: Diagnostic and prognostic histopathology system using morphometric indices

Abstract

Determining at least one of a prognosis or a therapy for a patient based on a stained tissue section of the patient. An image of a stained tissue section of a patient is processed by a processing device. A set of features values for a set of cell-based features is extracted from the processed image, and the processed image is associated with a particular cluster of a plurality of clusters based on the set of feature values, where the plurality of clusters is defined with respect to a feature space corresponding to the set of features.

Inventors:
; ; ;
Issue Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1179221
Patent Number(s):
9031306
Application Number:
13/886,213
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16H - HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16B - BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 May 02
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES; 97 MATHEMATICS AND COMPUTING

Citation Formats

Parvin, Bahram, Chang, Hang, Han, Ju, and Fontenay, Gerald V. Diagnostic and prognostic histopathology system using morphometric indices. United States: N. p., 2015. Web.
Parvin, Bahram, Chang, Hang, Han, Ju, & Fontenay, Gerald V. Diagnostic and prognostic histopathology system using morphometric indices. United States.
Parvin, Bahram, Chang, Hang, Han, Ju, and Fontenay, Gerald V. Tue . "Diagnostic and prognostic histopathology system using morphometric indices". United States. https://www.osti.gov/servlets/purl/1179221.
@article{osti_1179221,
title = {Diagnostic and prognostic histopathology system using morphometric indices},
author = {Parvin, Bahram and Chang, Hang and Han, Ju and Fontenay, Gerald V},
abstractNote = {Determining at least one of a prognosis or a therapy for a patient based on a stained tissue section of the patient. An image of a stained tissue section of a patient is processed by a processing device. A set of features values for a set of cell-based features is extracted from the processed image, and the processed image is associated with a particular cluster of a plurality of clusters based on the set of feature values, where the plurality of clusters is defined with respect to a feature space corresponding to the set of features.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {5}
}

Patent:

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Works referenced in this record:

Comparison of sparse coding and kernel methods for histopathological classification of gliobastoma multiforme
conference, March 2011

  • Han, Ju; Chang, Hang; Loss, Leandro
  • 2011 8th IEEE International Symposium on Biomedical Imaging (ISBI 2011), 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro
  • https://doi.org/10.1109/ISBI.2011.5872505

Iterative Tensor Voting for Perceptual Grouping of Ill-Defined Curvilinear Structures
journal, August 2011


Morphometic analysis of TCGA glioblastoma multiforme
journal, January 2011


Learning invariant features of tumor signatures
conference, May 2012

  • Le, Quoc V.; Han, Ju; Gray, Joe W.
  • 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012), 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)
  • https://doi.org/10.1109/ISBI.2012.6235544

Batch-invariant nuclear segmentation in whole mount histology sections
conference, May 2012

  • Chang, Hang; Loss, Leandro A.; Spellman, Paul T.
  • 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012), 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)
  • https://doi.org/10.1109/ISBI.2012.6235683

Molecular bases of morphometric composition in Glioblastoma multiforme
conference, May 2012

  • Han, Ju; Chang, Hang; Fontenay, Gerald V.
  • 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012), 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)
  • https://doi.org/10.1109/ISBI.2012.6235889