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Title: Rapid detection and identification of energetic materials with surface enhanced raman spectrometry (SERS)

Abstract

In one embodiment, a system includes a plurality of metal nanoparticles functionalized with a plurality of organic molecules tethered thereto, wherein the plurality of organic molecules preferentially interact with one or more analytes when placed in proximity therewith. According to another embodiment, a method for detecting analytes includes contacting a fluid having one or more analytes of interest therein with a plurality of metal nanoparticles, each metal nanoparticle having a plurality of organic molecules tethered thereto, and detecting Raman scattering from an analyte of interest from the fluid, the analyte interacting with one or more of the plurality of organic molecules. In another embodiment, a method includes chemically modifying a plurality of cyclodextrin molecules at a primary hydroxyl moiety to create a chemical handle, and tethering the plurality of cyclodextrin molecules to a metal nanoparticle using the chemical handle. Other systems and methods for detecting analytes are also described.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1178253
Patent Number(s):
9,012,241
Application Number:
12/844,778
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2010 Jul 27
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Han, Thomas Yong-Jin, Valdez, Carlos A, Olson, Tammy Y, Kim, Sung Ho, and Satcher, Jr., Joe H. Rapid detection and identification of energetic materials with surface enhanced raman spectrometry (SERS). United States: N. p., 2015. Web.
Han, Thomas Yong-Jin, Valdez, Carlos A, Olson, Tammy Y, Kim, Sung Ho, & Satcher, Jr., Joe H. Rapid detection and identification of energetic materials with surface enhanced raman spectrometry (SERS). United States.
Han, Thomas Yong-Jin, Valdez, Carlos A, Olson, Tammy Y, Kim, Sung Ho, and Satcher, Jr., Joe H. Tue . "Rapid detection and identification of energetic materials with surface enhanced raman spectrometry (SERS)". United States. https://www.osti.gov/servlets/purl/1178253.
@article{osti_1178253,
title = {Rapid detection and identification of energetic materials with surface enhanced raman spectrometry (SERS)},
author = {Han, Thomas Yong-Jin and Valdez, Carlos A and Olson, Tammy Y and Kim, Sung Ho and Satcher, Jr., Joe H},
abstractNote = {In one embodiment, a system includes a plurality of metal nanoparticles functionalized with a plurality of organic molecules tethered thereto, wherein the plurality of organic molecules preferentially interact with one or more analytes when placed in proximity therewith. According to another embodiment, a method for detecting analytes includes contacting a fluid having one or more analytes of interest therein with a plurality of metal nanoparticles, each metal nanoparticle having a plurality of organic molecules tethered thereto, and detecting Raman scattering from an analyte of interest from the fluid, the analyte interacting with one or more of the plurality of organic molecules. In another embodiment, a method includes chemically modifying a plurality of cyclodextrin molecules at a primary hydroxyl moiety to create a chemical handle, and tethering the plurality of cyclodextrin molecules to a metal nanoparticle using the chemical handle. Other systems and methods for detecting analytes are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {4}
}

Patent:

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Works referenced in this record:

Synthesis of Oligo(ethylenediamino)- β -Cyclodextrin Modified Gold Nanoparticle as a DNA Concentrator
journal, January 2007

  • Wang, Hao; Chen, Yong; Li, Xiao-Yun
  • Molecular Pharmaceutics, Vol. 4, Issue 2
  • DOI: 10.1021/mp060045s

Cyclodextrin-Modified Gold Nanospheres
journal, April 2000

  • Liu, Jian; Ong, Winston; Román, Esteban
  • Langmuir, Vol. 16, Issue 7
  • DOI: 10.1021/la991519f

Tailoring β-Cyclodextrin for DNA Complexation and Delivery by Homogeneous Functionalization at the Secondary Face
journal, November 2008

  • Ortega-Caballero, Fernando; Mellet, Carmen Ortiz; Le Gourriérec, Loïc
  • Organic Letters, Vol. 10, Issue 22
  • DOI: 10.1021/ol802081z

Water-soluble platinum and palladium nanoparticles modified with thiolated β-cyclodextrin
journal, January 2000

  • Alvarez, Julio; Liu, Jian; Román, Esteban
  • Chemical Communications, Issue 13
  • DOI: 10.1039/b002423f

Photo–Fenton treatment of TNT contaminated soil extract solutions obtained by soil flushing with cyclodextrin
journal, March 2006


Self-Assembled Monolayers of α-Cyclodextrin Derivatives on Gold and Their Host−Guest Behavior
journal, February 2009

  • Perl, András; Kumprecht, Lukáš; Kraus, Tomáš
  • Langmuir, Vol. 25, Issue 3
  • DOI: 10.1021/la803673b

Gold Nanoparticle Based Label-Free SERS Probe for Ultrasensitive and Selective Detection of Trinitrotoluene
journal, September 2009

  • Dasary, Samuel S. R.; Singh, Anant Kumar; Senapati, Dulal
  • Journal of the American Chemical Society, Vol. 131, Issue 38
  • DOI: 10.1021/ja905134d

Nanotechnology-Based Detection of Explosives and Biological Agents Simulants
journal, June 2008

  • Primera-Pedrozo, Oliva M.; Jerez-Rozo, Jackeline I.; De La Cruz-Montoya, Edwin
  • IEEE Sensors Journal, Vol. 8, Issue 6
  • DOI: 10.1109/JSEN.2008.923936

Surface-enhanced Raman spectroscopy for homeland defense
conference, March 2004

  • Spencer, Kevin M.; Sylvia, James M.; Marren, Peter J.
  • Optical Technologies for Industrial, Environmental, and Biological Sensing, SPIE Proceedings
  • DOI: 10.1117/12.514845

Raman spectroscopy of illicit substances
conference, October 2007

  • Stokes, Robert J.; Faulds, Karen; Smith, W. Ewen
  • Optics/Photonics in Security and Defence, SPIE Proceedings
  • DOI: 10.1117/12.739081

Surface enhanced Raman spectroscopy on chip
conference, March 2008

  • Hubner, Jorg; Anhøj, Thomas; Pedersen, Sarah
  • Integrated Optoelectronic Devices 2008, SPIE Proceedings
  • DOI: 10.1117/12.761076

SERS detection of the nuclear weapons explosive triaminotrinitrobenzene
conference, February 2002

  • Janni, James A.; Sylvia, James M.; Clauson, Susan L.
  • Environmental and Industrial Sensing, SPIE Proceedings
  • DOI: 10.1117/12.455742

Innovative smart micro sensors for Army weaponry applications
conference, April 2008

  • Ruffin, Paul B.; Brantley, Christina; Edwards, Eugene
  • The 15th International Symposium on: Smart Structures and Materials & Nondestructive Evaluation and Health Monitoring, SPIE Proceedings
  • DOI: 10.1117/12.784973

Nanoparticle-Decorated Nanocanals for Surface-Enhanced Raman Scattering
journal, November 2008


Surface-Enhanced Raman Detection of 2,4-Dinitrotoluene Impurity Vapor as a Marker To Locate Landmines
journal, December 2000

  • Sylvia, James M.; Janni, James A.; Klein, J. D.
  • Analytical Chemistry, Vol. 72, Issue 23
  • DOI: 10.1021/ac0006573

Remote chemical sensing with quantum cascade lasers
conference, September 2004

  • Harper, Warren W.; Strasburg, Jana D.
  • Defense and Security, SPIE Proceedings
  • DOI: 10.1117/12.541699

Progress in plasmonic engineering of surface-enhanced Raman-scattering substrates toward ultra-trace analysis
journal, July 2005


Nanoporous Membranes with Mixed Nanoclusters for Raman-Based Label-Free Monitoring of Peroxide Compounds
journal, July 2009

  • Chang, Sehoon; Ko, Hyunhyub; Singamaneni, Srikanth
  • Analytical Chemistry, Vol. 81, Issue 14
  • DOI: 10.1021/ac900537d

Detection of residual traces of explosives by surface enhanced Raman scattering using gold coated substrates produced by nanospheres imprint technique
conference, May 2008

  • Calzzani, Jr., F. A.; Sileshi, R.; Kassu, A.
  • SPIE Defense and Security Symposium, SPIE Proceedings
  • DOI: 10.1117/12.777072

Fingerprinting CBRNE materials using surface-enhanced Raman scattering
conference, May 2008

  • Bertone, Jane F.; Spencer, Kevin M.; Sylvia, James M.
  • SPIE Defense and Security Symposium, SPIE Proceedings
  • DOI: 10.1117/12.776713

Detection of explosive vapour using surface-enhanced Raman spectroscopy
journal, August 2009


Advances in land mine detection using surface-enhanced Raman spectroscopy
conference, August 1999

  • Spencer, Kevin M.; Sylvia, James M.; Janni, James A.
  • AeroSense '99, SPIE Proceedings
  • DOI: 10.1117/12.357060

Porous Substrates for Label-Free Molecular Level Detection of Nonresonant Organic Molecules
journal, December 2008

  • Ko, Hyunhyub; Chang, Sehoon; Tsukruk, Vladimir V.
  • ACS Nano, Vol. 3, Issue 1
  • DOI: 10.1021/nn800569f

Nanoparticle-Decorated Nanocanals for Surface-Enhanced Raman Scattering
journal, November 2008


Enhanced raman spectroscopy of 2,4,6-TNT in anatase and rutile titania nanocrystals
conference, May 2006

  • De La Cruz-Montoya, Edwin; Jeréz, Jaqueline I.; Balaguera-Gelves, Marcia
  • Defense and Security Symposium, SPIE Proceedings
  • DOI: 10.1117/12.666129

Silver metal colloidal film on a flexible polymer substrate
conference, May 2006

  • del Rocío Balaguera Gelves, Marcia; El Burai-Félix, Alia; De La Cruz-Montoya, Edwin
  • Defense and Security Symposium, SPIE Proceedings
  • DOI: 10.1117/12.666437

A nanoengineered sensor to detect vibrational modes of warfare agents/explosives using surface-enhanced Raman scattering
conference, September 2004

  • Bertone, Jane F.; Cordeiro, Kellie L.; Sylvia, James M.
  • Defense and Security, SPIE Proceedings
  • DOI: 10.1117/12.542164