Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures
Abstract
Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1177079
- Patent Number(s):
- 8993327
- Application Number:
- 10/408,294
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2003 Apr 07
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 77 NANOSCIENCE AND NANOTECHNOLOGY
Citation Formats
McKnight, Timothy E, Melechko, Anatoli V, Griffin, Guy D, Guillorn, Michael A, Merkulov, Vladimir L, and Simpson, Michael L. Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures. United States: N. p., 2015.
Web.
McKnight, Timothy E, Melechko, Anatoli V, Griffin, Guy D, Guillorn, Michael A, Merkulov, Vladimir L, & Simpson, Michael L. Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures. United States.
McKnight, Timothy E, Melechko, Anatoli V, Griffin, Guy D, Guillorn, Michael A, Merkulov, Vladimir L, and Simpson, Michael L. Tue .
"Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures". United States. https://www.osti.gov/servlets/purl/1177079.
@article{osti_1177079,
title = {Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures},
author = {McKnight, Timothy E and Melechko, Anatoli V and Griffin, Guy D and Guillorn, Michael A and Merkulov, Vladimir L and Simpson, Michael L},
abstractNote = {Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 31 00:00:00 EDT 2015},
month = {Tue Mar 31 00:00:00 EDT 2015}
}
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