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Title: Samarium-145 and its use as a radiation source

Abstract

The present invention covers a new radiation source, samarium-145, with radiation energies slightly above those of I-125 and a half-life of 340 days. The samarium-145 source is produced by neutron irradiation of SM-144. This new source is useful as the implanted radiation source in photon activation therapy of malignant tumors to activate the stable I-127 contained in the IdUrd accumulated in the tumor, causing radiation sensitization and Auger cascades that irreperably damage the tumor cells. This new source is also useful as a brachytherapy source.

Inventors:
; ;
Issue Date:
Research Org.:
US Department of Energy (USDOE), Washington DC (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1176605
Patent Number(s):
H000669
Assignee:
United States Of America, Department Of Energy
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE

Citation Formats

Fairchild, Ralph G., Laster, Brenda H., and Packer, Samuel. Samarium-145 and its use as a radiation source. United States: N. p., 1989. Web.
Fairchild, Ralph G., Laster, Brenda H., & Packer, Samuel. Samarium-145 and its use as a radiation source. United States.
Fairchild, Ralph G., Laster, Brenda H., and Packer, Samuel. Tue . "Samarium-145 and its use as a radiation source". United States. https://www.osti.gov/servlets/purl/1176605.
@article{osti_1176605,
title = {Samarium-145 and its use as a radiation source},
author = {Fairchild, Ralph G. and Laster, Brenda H. and Packer, Samuel},
abstractNote = {The present invention covers a new radiation source, samarium-145, with radiation energies slightly above those of I-125 and a half-life of 340 days. The samarium-145 source is produced by neutron irradiation of SM-144. This new source is useful as the implanted radiation source in photon activation therapy of malignant tumors to activate the stable I-127 contained in the IdUrd accumulated in the tumor, causing radiation sensitization and Auger cascades that irreperably damage the tumor cells. This new source is also useful as a brachytherapy source.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1989},
month = {9}
}