Samarium-145 and its use as a radiation source
Abstract
The present invention covers a new radiation source, samarium-145, with radiation energies slightly above those of I-125 and a half-life of 340 days. The samarium-145 source is produced by neutron irradiation of SM-144. This new source is useful as the implanted radiation source in photon activation therapy of malignant tumors to activate the stable I-127 contained in the IdUrd accumulated in the tumor, causing radiation sensitization and Auger cascades that irreperably damage the tumor cells. This new source is also useful as a brachytherapy source.
- Inventors:
- Issue Date:
- Research Org.:
- Brookhaven National Laboratory (BNL), Upton, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176605
- Patent Number(s):
- H000669
- Application Number:
- 06/938839
- Assignee:
- United States Of America, Department Of Energy
- DOE Contract Number:
- AC02-76CH00016
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1986 Dec 08
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE
Citation Formats
Fairchild, Ralph G., Laster, Brenda H., and Packer, Samuel. Samarium-145 and its use as a radiation source. United States: N. p., 1989.
Web.
Fairchild, Ralph G., Laster, Brenda H., & Packer, Samuel. Samarium-145 and its use as a radiation source. United States.
Fairchild, Ralph G., Laster, Brenda H., and Packer, Samuel. Tue .
"Samarium-145 and its use as a radiation source". United States. https://www.osti.gov/servlets/purl/1176605.
@article{osti_1176605,
title = {Samarium-145 and its use as a radiation source},
author = {Fairchild, Ralph G. and Laster, Brenda H. and Packer, Samuel},
abstractNote = {The present invention covers a new radiation source, samarium-145, with radiation energies slightly above those of I-125 and a half-life of 340 days. The samarium-145 source is produced by neutron irradiation of SM-144. This new source is useful as the implanted radiation source in photon activation therapy of malignant tumors to activate the stable I-127 contained in the IdUrd accumulated in the tumor, causing radiation sensitization and Auger cascades that irreperably damage the tumor cells. This new source is also useful as a brachytherapy source.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1989},
month = {9}
}
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Works referenced in this record:
Radiation Enhancement with Iodinated Deoxyuridine
journal, July 1982
- Fairchild, R. G.; Brill, A. B.; Ettinger, K. V.
- Investigative Radiology, Vol. 17, Issue 4