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Title: Actinium radioisotope products of enhanced purity

Abstract

A product includes actinium-225 (.sup.225Ac) and less than about 1 microgram (.mu.g) of iron (Fe) per millicurie (mCi) of actinium-225. The product may have a radioisotopic purity of greater than about 99.99 atomic percent (at %) actinium-225 and daughter isotopes of actinium-225, and may be formed by a method that includes providing a radioisotope mixture solution comprising at least one of uranium-233 (.sup.233U) and thorium-229 (.sup.229Th), extracting the at least one of uranium-233 and thorium-229 into an organic phase, substantially continuously contacting the organic phase with an aqueous phase, substantially continuously extracting actinium-225 into the aqueous phase, and purifying the actinium-225 from the aqueous phase. In some embodiments, the product may include less than about 1 nanogram (ng) of iron per millicurie (mCi) of actinium-225, and may include less than about 1 microgram (.mu.g) each of magnesium (Mg), Chromium (Cr), and manganese (Mn) per millicurie (mCi) of actinium-225.

Inventors:
; ; ;
Issue Date:
Research Org.:
Idaho National Laboratory (INL), Idaho Falls, ID (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1176357
Patent Number(s):
7736610
Application Number:
11/278,522
Assignee:
Battelle Energy Alliance, LLC (Idaho Falls, ID)
Patent Classifications (CPCs):
C - CHEMISTRY C22 - METALLURGY C22B - PRODUCTION AND REFINING OF METALS
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
DOE Contract Number:  
AC07-05ID14517
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
07 ISOTOPE AND RADIATION SOURCES; 62 RADIOLOGY AND NUCLEAR MEDICINE

Citation Formats

Meikrantz, David Herbert, Todd, Terry Allen, Tranter, Troy Joseph, and Horwitz, E. Philip. Actinium radioisotope products of enhanced purity. United States: N. p., 2010. Web.
Meikrantz, David Herbert, Todd, Terry Allen, Tranter, Troy Joseph, & Horwitz, E. Philip. Actinium radioisotope products of enhanced purity. United States.
Meikrantz, David Herbert, Todd, Terry Allen, Tranter, Troy Joseph, and Horwitz, E. Philip. Tue . "Actinium radioisotope products of enhanced purity". United States. https://www.osti.gov/servlets/purl/1176357.
@article{osti_1176357,
title = {Actinium radioisotope products of enhanced purity},
author = {Meikrantz, David Herbert and Todd, Terry Allen and Tranter, Troy Joseph and Horwitz, E. Philip},
abstractNote = {A product includes actinium-225 (.sup.225Ac) and less than about 1 microgram (.mu.g) of iron (Fe) per millicurie (mCi) of actinium-225. The product may have a radioisotopic purity of greater than about 99.99 atomic percent (at %) actinium-225 and daughter isotopes of actinium-225, and may be formed by a method that includes providing a radioisotope mixture solution comprising at least one of uranium-233 (.sup.233U) and thorium-229 (.sup.229Th), extracting the at least one of uranium-233 and thorium-229 into an organic phase, substantially continuously contacting the organic phase with an aqueous phase, substantially continuously extracting actinium-225 into the aqueous phase, and purifying the actinium-225 from the aqueous phase. In some embodiments, the product may include less than about 1 nanogram (ng) of iron per millicurie (mCi) of actinium-225, and may include less than about 1 microgram (.mu.g) each of magnesium (Mg), Chromium (Cr), and manganese (Mn) per millicurie (mCi) of actinium-225.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 15 00:00:00 EDT 2010},
month = {Tue Jun 15 00:00:00 EDT 2010}
}

Works referenced in this record:

Heavy Element Separation for Thorium-Uranium-Plutonium Fuels
book, April 1980


Production of actinium-225 for alpha particle mediated radioimmunotherapy
journal, May 2005


Novel Extraction of Chromatographic Resins Based on Tetraalkyldiglycolamides: Characterization and Potential Applications
journal, May 2005