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Title: Method for the chemical separation of GE-68 from its daughter Ga-68

Abstract

The present invention is directed to a generator apparatus for separating a daughter gallium-68 radioisotope substantially free of impurities from a parent gernanium-68 radioisotope, including a first resin-containing column containing parent gernanium-68 radioisotope and daughter gallium-68 radioisotope, a source of first eluent connected to said first resin-containing column for separating daughter gallium-68 radioisotope from the first resin-containing column, said first eluent including citrate whereby the separated gallium is in the form of gallium citrate, a mixing space connected to said first resin-containing column for admixing a source of hydrochloric acid with said separated gallium citrate whereby gallium citrate is converted to gallium tetrachloride, a second resin-containing column for retention of gallium-68 tetrachloride, and, a source of second eluent connected to said second resin-containing column for eluting the daughter gallium-68 radioisotope from said second resin-containing column.

Inventors:
;
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1176326
Patent Number(s):
7,728,310
Application Number:
12/151,865
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM) LANL
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 62 RADIOLOGY AND NUCLEAR MEDICINE

Citation Formats

Fitzsimmons, Jonathan M., and Atcher, Robert W. Method for the chemical separation of GE-68 from its daughter Ga-68. United States: N. p., 2010. Web.
Fitzsimmons, Jonathan M., & Atcher, Robert W. Method for the chemical separation of GE-68 from its daughter Ga-68. United States.
Fitzsimmons, Jonathan M., and Atcher, Robert W. Tue . "Method for the chemical separation of GE-68 from its daughter Ga-68". United States. https://www.osti.gov/servlets/purl/1176326.
@article{osti_1176326,
title = {Method for the chemical separation of GE-68 from its daughter Ga-68},
author = {Fitzsimmons, Jonathan M. and Atcher, Robert W.},
abstractNote = {The present invention is directed to a generator apparatus for separating a daughter gallium-68 radioisotope substantially free of impurities from a parent gernanium-68 radioisotope, including a first resin-containing column containing parent gernanium-68 radioisotope and daughter gallium-68 radioisotope, a source of first eluent connected to said first resin-containing column for separating daughter gallium-68 radioisotope from the first resin-containing column, said first eluent including citrate whereby the separated gallium is in the form of gallium citrate, a mixing space connected to said first resin-containing column for admixing a source of hydrochloric acid with said separated gallium citrate whereby gallium citrate is converted to gallium tetrachloride, a second resin-containing column for retention of gallium-68 tetrachloride, and, a source of second eluent connected to said second resin-containing column for eluting the daughter gallium-68 radioisotope from said second resin-containing column.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {6}
}

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