Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides
Abstract
New modifiers were synthesized for incorporation of a methacrylic function in 3'-, 5'- and internal positions of oligonucleotides during solid phase synthesis. A modifier was used for synthesis of 5'-methacrylated oligonucleotides for preparation of microarrays by a co-polymerization method.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176258
- Patent Number(s):
- 7705136
- Application Number:
- 11/066,791
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Classifications (CPCs):
-
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07H - SUGARS
- DOE Contract Number:
- W-31-109-ENG-38
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Golova, Julia B., and Chernov, Boris K. Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides. United States: N. p., 2010.
Web.
Golova, Julia B., & Chernov, Boris K. Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides. United States.
Golova, Julia B., and Chernov, Boris K. Tue .
"Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides". United States. https://www.osti.gov/servlets/purl/1176258.
@article{osti_1176258,
title = {Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides},
author = {Golova, Julia B. and Chernov, Boris K.},
abstractNote = {New modifiers were synthesized for incorporation of a methacrylic function in 3'-, 5'- and internal positions of oligonucleotides during solid phase synthesis. A modifier was used for synthesis of 5'-methacrylated oligonucleotides for preparation of microarrays by a co-polymerization method.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {4}
}
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