Method of identifying hairpin DNA probes by partial fold analysis
Abstract
Methods of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.
- Inventors:
- Issue Date:
- Research Org.:
- University Of Rochester, Rochester, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176186
- Patent Number(s):
- 7442510
- Application Number:
- 11/553,904
- Assignee:
- University Of Rochester (Rochester, NY)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- FG02-02ER63410
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2006 Oct 27
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES
Citation Formats
Miller, Benjamin L., and Strohsahl, Christopher M. Method of identifying hairpin DNA probes by partial fold analysis. United States: N. p., 2008.
Web.
Miller, Benjamin L., & Strohsahl, Christopher M. Method of identifying hairpin DNA probes by partial fold analysis. United States.
Miller, Benjamin L., and Strohsahl, Christopher M. Tue .
"Method of identifying hairpin DNA probes by partial fold analysis". United States. https://www.osti.gov/servlets/purl/1176186.
@article{osti_1176186,
title = {Method of identifying hairpin DNA probes by partial fold analysis},
author = {Miller, Benjamin L. and Strohsahl, Christopher M.},
abstractNote = {Methods of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {10}
}
Works referenced in this record:
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Thermodynamic basis of the enhanced specificity of structured DNA probes
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