NMR and MRI apparatus and method
Abstract
Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. Additional signal to noise benefits are obtained by use of a low noise polarization coil, comprising litz wire or superconducting materials. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176131
- Patent Number(s):
- 7187169
- Application Number:
- 10/980,984
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01R - MEASURING ELECTRIC VARIABLES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2004 Nov 03
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 36 MATERIALS SCIENCE
Citation Formats
Clarke, John, Kelso, Nathan, Lee, SeungKyun, Moessle, Michael, Myers, Whittier, McDermott, Robert, ten Haken, Bernard, Pines, Alexander, and Trabesinger, Andreas. NMR and MRI apparatus and method. United States: N. p., 2007.
Web.
Clarke, John, Kelso, Nathan, Lee, SeungKyun, Moessle, Michael, Myers, Whittier, McDermott, Robert, ten Haken, Bernard, Pines, Alexander, & Trabesinger, Andreas. NMR and MRI apparatus and method. United States.
Clarke, John, Kelso, Nathan, Lee, SeungKyun, Moessle, Michael, Myers, Whittier, McDermott, Robert, ten Haken, Bernard, Pines, Alexander, and Trabesinger, Andreas. Tue .
"NMR and MRI apparatus and method". United States. https://www.osti.gov/servlets/purl/1176131.
@article{osti_1176131,
title = {NMR and MRI apparatus and method},
author = {Clarke, John and Kelso, Nathan and Lee, SeungKyun and Moessle, Michael and Myers, Whittier and McDermott, Robert and ten Haken, Bernard and Pines, Alexander and Trabesinger, Andreas},
abstractNote = {Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. Additional signal to noise benefits are obtained by use of a low noise polarization coil, comprising litz wire or superconducting materials. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {3}
}
Works referenced in this record:
Liquid-State NMR and Scalar Couplings in Microtesla Magnetic Fields
journal, March 2002
- McDermott, R.
- Science, Vol. 295, Issue 5563
Application of superconducting quantum interference devices to nuclear magnetic resonance
journal, January 1998
- Greenberg, Ya. S.
- Reviews of Modern Physics, Vol. 70, Issue 1