Injectible bodily prosthetics employing methacrylic copolymer gels
Abstract
The present invention provides novel block copolymers as structural supplements for injectible bodily prosthetics employed in medical or cosmetic procedures. The invention also includes the use of such block copolymers as nucleus pulposus replacement materials for the treatment of degenerative disc disorders and spinal injuries. The copolymers are constructed by polymerization of a tertiary amine methacrylate with either a (poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) polymer, such as the commercially available Pluronic.RTM. polymers, or a poly(ethylene glycol) methyl ether polymer.
- Inventors:
- Issue Date:
- Research Org.:
- Ames Laboratory (AMES), Ames, IA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176127
- Patent Number(s):
- 7183369
- Application Number:
- 10/367,414
- Assignee:
- Iowa State University Research Foundation, Inc. (Ames, IA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61L - METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08F - MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- DOE Contract Number:
- W-7405-ENG-82
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2003 Feb 14
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 60 APPLIED LIFE SCIENCES
Citation Formats
Mallapragada, Surya K., and Anderson, Brian C. Injectible bodily prosthetics employing methacrylic copolymer gels. United States: N. p., 2007.
Web.
Mallapragada, Surya K., & Anderson, Brian C. Injectible bodily prosthetics employing methacrylic copolymer gels. United States.
Mallapragada, Surya K., and Anderson, Brian C. Tue .
"Injectible bodily prosthetics employing methacrylic copolymer gels". United States. https://www.osti.gov/servlets/purl/1176127.
@article{osti_1176127,
title = {Injectible bodily prosthetics employing methacrylic copolymer gels},
author = {Mallapragada, Surya K. and Anderson, Brian C.},
abstractNote = {The present invention provides novel block copolymers as structural supplements for injectible bodily prosthetics employed in medical or cosmetic procedures. The invention also includes the use of such block copolymers as nucleus pulposus replacement materials for the treatment of degenerative disc disorders and spinal injuries. The copolymers are constructed by polymerization of a tertiary amine methacrylate with either a (poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) polymer, such as the commercially available Pluronic.RTM. polymers, or a poly(ethylene glycol) methyl ether polymer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {2}
}
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Works referenced in this record:
Synthesis of Controlled Structure Water-Soluble Diblock Copolymers via Oxyanionic Polymerization
journal, March 1999
- Vamvakaki, M.; Billingham, N. C.; Armes, S. P.
- Macromolecules, Vol. 32, Issue 6
Structure of pH-Dependent Block Copolymer Micelles: Charge and Ionic Strength Dependence
journal, October 2002
- Lee, Albert S.; Bütün, Vural; Vamvakaki, M.
- Macromolecules, Vol. 35, Issue 22