skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: pH-sensitive methacrylic copolymers and the production thereof

Abstract

The present invention provides novel multi-functional methacrylic copolymers that exhibit cationic pH-sensitive behavior as well as good water solubility under acidic conditions. The copolymers are constructed from tertiary amine methacrylates and poly(ethylene glycol) containing methacrylates. The copolymers are useful as gene vectors, pharmaceutical carriers, and in protein separation applications.

Inventors:
; ; ;
Issue Date:
Research Org.:
Iowa State Univ., Ames, IA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1176067
Patent Number(s):
7160971
Application Number:
11/284,502
Assignee:
Iowa State University Research Foundation (Ames, IA)
Patent Classifications (CPCs):
C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08F - MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
DOE Contract Number:  
W-7405-ENG-82
Resource Type:
Patent
Resource Relation:
Patent File Date: 2005 Nov 22
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Mallapragada, Surya K., Anderson, Brian C., Bloom, Paul D., and Sheares Ashby, Valerie V. pH-sensitive methacrylic copolymers and the production thereof. United States: N. p., 2007. Web.
Mallapragada, Surya K., Anderson, Brian C., Bloom, Paul D., & Sheares Ashby, Valerie V. pH-sensitive methacrylic copolymers and the production thereof. United States.
Mallapragada, Surya K., Anderson, Brian C., Bloom, Paul D., and Sheares Ashby, Valerie V. Tue . "pH-sensitive methacrylic copolymers and the production thereof". United States. https://www.osti.gov/servlets/purl/1176067.
@article{osti_1176067,
title = {pH-sensitive methacrylic copolymers and the production thereof},
author = {Mallapragada, Surya K. and Anderson, Brian C. and Bloom, Paul D. and Sheares Ashby, Valerie V.},
abstractNote = {The present invention provides novel multi-functional methacrylic copolymers that exhibit cationic pH-sensitive behavior as well as good water solubility under acidic conditions. The copolymers are constructed from tertiary amine methacrylates and poly(ethylene glycol) containing methacrylates. The copolymers are useful as gene vectors, pharmaceutical carriers, and in protein separation applications.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {1}
}

Patent:

Save / Share:

Works referenced in this record: