Very fast doped LaBr3 scintillators and time-of-flight PET

Shah, Kanai S.

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Title: Very fast doped LaBr₃ scintillators and time-of-flight PET

Abstract

The present invention concerns very fast scintillator materials capable of resolving the position of an annihilation event within a portion of a human body cross-section. In one embodiment, the scintillator material comprises LaBr₃ doped with cerium. Particular attention is drawn to LaBr₃ doped with a quantity of Ce that is chosen for improving the timing properties, in particular the rise time and resultant timing resolution of the scintillator, and locational capabilities of the scintillator.

Inventors:: Shah, Kanai S.

Issue Date:: 2006-10-31

Research Org.:: Oak Ridge Y-12 Plant (Y-12), Oak Ridge, TN (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Radiation Monitoring Devices, Inc., Watertown, MA (United States)

Sponsoring Org.:: USDOE; National Institutes of Health (NIH)

OSTI Identifier:: 1175971

Patent Number(s):: 7129494

Application Number:: 10/948,913

Assignee:: Radiation Monitoring Devices, Inc. (Watertown, MA)

Patent Classifications (CPCs):: C - CHEMISTRY C09 - DYES C09K - MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE

C - CHEMISTRY C30 - CRYSTAL GROWTH C30B - SINGLE-CRYSTAL-GROWTH

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C - CHEMISTRY C09 - DYES C09K - MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
C09K11/7772 - {Halogenides

C - CHEMISTRY C30 - CRYSTAL GROWTH C30B - SINGLE-CRYSTAL-GROWTH
C30B11/00 - Single-crystal growth by normal freezing or freezing under temperature gradient, e.g. Bridgman-Stockbarger method
C30B29/12 - Halides

G - PHYSICS G01 - MEASURING G01T - MEASUREMENT OF NUCLEAR OR X-RADIATION
G01T1/172 - with coincidence circuit arrangements

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DOE Contract Number:: AC03-76SF00098; R01-CA67911; P01-HL25840

Resource Type:: Patent

Resource Relation:: Patent File Date: 2004 Sep 23

Country of Publication:: United States

Language:: English

Subject:: 36 MATERIALS SCIENCE

Citation Formats


                    Shah, Kanai S. Very fast doped LaBr3 scintillators and time-of-flight PET.  United States: N. p., 2006. 
        Web.

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                    Shah, Kanai S. Very fast doped LaBr3 scintillators and time-of-flight PET.  United States.

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                    Shah, Kanai S. Tue .  
        "Very fast doped LaBr3 scintillators and time-of-flight PET".  United States.  https://www.osti.gov/servlets/purl/1175971.

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@article{osti_1175971,

  title        = {Very fast doped LaBr3 scintillators and time-of-flight PET},

  author       = {Shah, Kanai S.},

  abstractNote = {The present invention concerns very fast scintillator materials capable of resolving the position of an annihilation event within a portion of a human body cross-section. In one embodiment, the scintillator material comprises LaBr3 doped with cerium. Particular attention is drawn to LaBr3 doped with a quantity of Ce that is chosen for improving the timing properties, in particular the rise time and resultant timing resolution of the scintillator, and locational capabilities of the scintillator.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2006},

  month        = {10}

}

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Works referenced in this record:

Positron emission tomography provides molecular imaging of biological processes
journal, August 2000

Phelps, M. E.
Proceedings of the National Academy of Sciences, Vol. 97, Issue 16
https://doi.org/10.1073/pnas.97.16.9226

Measurement of the Time Dependence of Scintillation Intensity by a Delayed‐Coincidence Method
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Bollinger, L. M.; Thomas, G. E.
Review of Scientific Instruments, Vol. 32, Issue 9, p. 1044-1050
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Dynamic Imaging with High Resolution Time-of-Flight PET Camera - TOFPET I
journal, January 1984

Mullani, N. A.; Gaeta, J.; Yerian, K.
IEEE Transactions on Nuclear Science, Vol. 31, Issue 1
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High-energy-resolution scintillator: Ce³⁺ activated LaBr₃
journal, September 2001

van Loef, E. V. D.; Dorenbos, P.; van Eijk, C. W. E.
Applied Physics Letters, Vol. 79, Issue 10, p. 1573-1575
https://doi.org/10.1063/1.1385342

LuAlO/sub 3/:Ce-a high density, high speed scintillator for gamma detection
journal, January 1995

Moses, W. W.; Derenzo, S. E.; Fyodorov, A.
IEEE Transactions on Nuclear Science, Vol. 42, Issue 4
https://doi.org/10.1109/23.467837

Time-of-flight positron imaging and the resolution improvement by an iterative method
journal, January 1989

Yamamoto, M.; Nohara, N.; Tanaka, E.
IEEE Transactions on Nuclear Science, Vol. 36, Issue 1
https://doi.org/10.1109/23.34592

Gamma ray spectroscopy and timing using LSO and PIN photodiodes
journal, January 1995

Moses, W. W.; Derenzo, S. E.; Melcher, C. L.
IEEE Transactions on Nuclear Science, Vol. 42, Issue 4
https://doi.org/10.1109/23.467907

Time-of-flight PET
journal, July 1998

Lewellen, Tom K.
Seminars in Nuclear Medicine, Vol. 28, Issue 3
https://doi.org/10.1016/S0001-2998(98)80031-7

Scintillation properties of RbGd/sub 2/Br/sub 7/:Ce. Advantages and limitations
journal, January 1999

Guillot-Noel, O.; van't Spijker, J. C.; de Haas, J. T. M.
IEEE Transactions on Nuclear Science, Vol. 46, Issue 5
https://doi.org/10.1109/23.795803

Performance measurements of the SP3000/UW time-of-flight positron emission tomograph
journal, February 1988

Lewellen, T. K.; Bice, A. N.; Harrison, R. L.
IEEE Transactions on Nuclear Science, Vol. 35, Issue 1
https://doi.org/10.1109/23.12808

Delay Line Readouts for High Purity Germanium Medical Imaging Cameras
journal, January 1974

Kaufman, Leon; Camp, David C.; McQuaid, James H.
IEEE Transactions on Nuclear Science, Vol. 21, Issue 1
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Prospects for time-of-flight PET using LSO scintillator
journal, June 1999

Moses, W. W.; Derenzo, S. E.
IEEE Transactions on Nuclear Science, Vol. 46, Issue 3
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LaBr/sub 3/:Ce scintillators for gamma ray spectroscopy
conference, January 2003

Shah, K. S.; Glodo, J.; Klugerman, M.
2002 IEEE Nuclear Science Symposium Conference Record
https://doi.org/10.1109/NSSMIC.2002.1239275

Characteristics of Small Barium Fluoride (BaF2) Scintillator for High Intrinsic Resolution Time-of-Flight Positron Emission Tomography
journal, January 1984

Wong, Wai-Hoi; Mullani, Nizar A.; Wardworth, Gary
IEEE Transactions on Nuclear Science, Vol. 31, Issue 1
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Scintillation properties of LaCl/sub 3/:Ce/sup 3+/ crystals: fast, efficient, and high-energy resolution scintillators
journal, June 2001

van Loef, E. V. D.; Dorenbos, L. P.; van Eijk, C. W. E.
IEEE Transactions on Nuclear Science, Vol. 48, Issue 3
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Image quality assessment of LaBr ₃ -based whole-body 3D PET scanners: a Monte Carlo evaluation
journal, September 2004

Surti, S.; Karp, J. S.; Muehllehner, G.
Physics in Medicine and Biology, Vol. 49, Issue 19
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Non-proportionality in the scintillation response and the energy resolution obtainable with scintillation crystals
journal, January 1995

Dorenbos, P.; de Haas, J. T. M.; van Eijk, C. W. E.
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Similar Records

Title: Very fast doped LaBr3 scintillators and time-of-flight PET

Abstract

Citation Formats

Positron emission tomography provides molecular imaging of biological processes journal, August 2000

Measurement of the Time Dependence of Scintillation Intensity by a Delayed‐Coincidence Method journal, September 1961

Dynamic Imaging with High Resolution Time-of-Flight PET Camera - TOFPET I journal, January 1984

High-energy-resolution scintillator: Ce3+ activated LaBr3 journal, September 2001

LuAlO/sub 3/:Ce-a high density, high speed scintillator for gamma detection journal, January 1995

Time-of-flight positron imaging and the resolution improvement by an iterative method journal, January 1989

Gamma ray spectroscopy and timing using LSO and PIN photodiodes journal, January 1995

Time-of-flight PET journal, July 1998

Scintillation properties of RbGd/sub 2/Br/sub 7/:Ce. Advantages and limitations journal, January 1999

Performance measurements of the SP3000/UW time-of-flight positron emission tomograph journal, February 1988

Delay Line Readouts for High Purity Germanium Medical Imaging Cameras journal, January 1974

Prospects for time-of-flight PET using LSO scintillator journal, June 1999

LaBr/sub 3/:Ce scintillators for gamma ray spectroscopy conference, January 2003

Characteristics of Small Barium Fluoride (BaF2) Scintillator for High Intrinsic Resolution Time-of-Flight Positron Emission Tomography journal, January 1984

Scintillation properties of LaCl/sub 3/:Ce/sup 3+/ crystals: fast, efficient, and high-energy resolution scintillators journal, June 2001

Image quality assessment of LaBr 3 -based whole-body 3D PET scanners: a Monte Carlo evaluation journal, September 2004

Non-proportionality in the scintillation response and the energy resolution obtainable with scintillation crystals journal, January 1995

Title: Very fast doped LaBr₃ scintillators and time-of-flight PET

Positron emission tomography provides molecular imaging of biological processes
journal, August 2000

Measurement of the Time Dependence of Scintillation Intensity by a Delayed‐Coincidence Method
journal, September 1961

Dynamic Imaging with High Resolution Time-of-Flight PET Camera - TOFPET I
journal, January 1984

High-energy-resolution scintillator: Ce³⁺ activated LaBr₃
journal, September 2001

LuAlO/sub 3/:Ce-a high density, high speed scintillator for gamma detection
journal, January 1995

Time-of-flight positron imaging and the resolution improvement by an iterative method
journal, January 1989

Gamma ray spectroscopy and timing using LSO and PIN photodiodes
journal, January 1995

Time-of-flight PET
journal, July 1998

Scintillation properties of RbGd/sub 2/Br/sub 7/:Ce. Advantages and limitations
journal, January 1999

Performance measurements of the SP3000/UW time-of-flight positron emission tomograph
journal, February 1988

Delay Line Readouts for High Purity Germanium Medical Imaging Cameras
journal, January 1974

Prospects for time-of-flight PET using LSO scintillator
journal, June 1999

LaBr/sub 3/:Ce scintillators for gamma ray spectroscopy
conference, January 2003

Characteristics of Small Barium Fluoride (BaF2) Scintillator for High Intrinsic Resolution Time-of-Flight Positron Emission Tomography
journal, January 1984

Scintillation properties of LaCl/sub 3/:Ce/sup 3+/ crystals: fast, efficient, and high-energy resolution scintillators
journal, June 2001

Image quality assessment of LaBr ₃ -based whole-body 3D PET scanners: a Monte Carlo evaluation
journal, September 2004

Non-proportionality in the scintillation response and the energy resolution obtainable with scintillation crystals
journal, January 1995