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Title: Methods to alter levels of a DNA repair protein

Abstract

An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

Inventors:
; ; ;
Issue Date:
Research Org.:
Wisconsin Alumni Research Foundation, Madison, WI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175948
Patent Number(s):
7122343
Application Number:
09/837,138
Assignee:
Wisconsin Alumni Research Foundation
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A01 - AGRICULTURE A01K - ANIMAL HUSBANDRY
DOE Contract Number:  
4459-011502
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Petrini, John H., Morgan, William Francis, Maser, Richard Scott, and Carney, James Patrick. Methods to alter levels of a DNA repair protein. United States: N. p., 2006. Web.
Petrini, John H., Morgan, William Francis, Maser, Richard Scott, & Carney, James Patrick. Methods to alter levels of a DNA repair protein. United States.
Petrini, John H., Morgan, William Francis, Maser, Richard Scott, and Carney, James Patrick. Tue . "Methods to alter levels of a DNA repair protein". United States. https://www.osti.gov/servlets/purl/1175948.
@article{osti_1175948,
title = {Methods to alter levels of a DNA repair protein},
author = {Petrini, John H. and Morgan, William Francis and Maser, Richard Scott and Carney, James Patrick},
abstractNote = {An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2006},
month = {10}
}

Works referenced in this record:

Production of pharmaceutical proteins from transgenic animals
journal, May 1994


Targeting the mouse genome: a compendium of knockouts (part I)
journal, June 1995


Knockout Mice
journal, April 1996


Analysis of the 5′ Region ofPMS2Reveals Heterogeneous Transcripts and a Novel Overlapping Gene
journal, September 1995


Transgenic and knock-out models for studying DNA repair
journal, January 1995


hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.
journal, October 1997


Xpaknockout mice
journal, October 1996


The nucleic acid of simian virus 40
journal, November 1964


A New Connection at Human Telomeres: Association of the Mre11 Complex with TRF2
journal, January 2000


Targeting the mouse genome: a compendium of knockouts (part II)
journal, July 1995


The Transformation Capacity of Early SV40 DNA Fragments
book, January 1985


Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
journal, July 2000


Isolation and Characterization of the Human MRE11 Homologue
journal, September 1995


Expression of RAD4 Gene of Saccharomyces cerevisiae That Can Be Propagated in Escherichia coli without Inactivation
journal, May 1993


Gene therapy - promises, problems and prospects
journal, September 1997