Title: Spatiotemporal and geometric optimization of sensor arrays for detecting analytes fluids

Abstract

Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed.

Inventors:

Lewis, Nathan S.; Freund, Michael S.; Briglin, Shawn M.; Tokumaru, Phil; Martin, Charles R.; Mitchell, David T.

Issue Date:

Tue Oct 17 00:00:00 EDT 2006

Research Org.:

Univ. of Florida, Gainesville, FL (United States); The California Institute of Technology, Pasadena, CA (United States); Aerovironment, Inc., Monrovia, CA (United States)

Sponsoring Org.:

USDOE; Defense Advanced Research Projects Agency (DARPA); US Army Research Office (ARO); National Aeronautics and Space Administration (NASA)

OSTI Identifier:

1175945

Patent Number(s):

7122152

Application Number:

09/842,204

Assignee:

University of Florida (Gainesville, FL) ; The California Institute of Technology (Pasadena, CA) ; Aerovironment, Inc. (Monrovia, CA)

Patent Classifications (CPCs):

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N33/0031 - {comprising two or more sensors, e.g. a sensor array

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

Y10T29/49 - Method of mechanical manufacture
Y10T29/49002 - Electrical device making
Y10T436/11 - Automated chemical analysis
Y10T436/12 - Condition responsive control

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DOE Contract Number:  

FG03-98NV13367; DAAK-60-97-K-9503; DAAG55-97-1-0187; DAAG55-98-1-0266; NAS-1407

Resource Type:

Patent

Resource Relation:

Patent File Date: 2001 Apr 24

Country of Publication:

United States

Language:

English

Subject:

47 OTHER INSTRUMENTATION