SQUID detected NMR and MRI at ultralow fields
Abstract
Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1175923
- Patent Number(s):
- 7116102
- Application Number:
- 11/277,550
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01R - MEASURING ELECTRIC VARIABLES
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2006 Mar 27
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
Citation Formats
Clarke, John, McDermott, Robert, Pines, Alexander, and Trabesinger, Andreas Heinz. SQUID detected NMR and MRI at ultralow fields. United States: N. p., 2006.
Web.
Clarke, John, McDermott, Robert, Pines, Alexander, & Trabesinger, Andreas Heinz. SQUID detected NMR and MRI at ultralow fields. United States.
Clarke, John, McDermott, Robert, Pines, Alexander, and Trabesinger, Andreas Heinz. Tue .
"SQUID detected NMR and MRI at ultralow fields". United States. https://www.osti.gov/servlets/purl/1175923.
@article{osti_1175923,
title = {SQUID detected NMR and MRI at ultralow fields},
author = {Clarke, John and McDermott, Robert and Pines, Alexander and Trabesinger, Andreas Heinz},
abstractNote = {Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2006},
month = {10}
}
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