skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Cloning and expression of recombinant adhesive protein MEFP-2 of the blue mussel, Mytilus edulis

Abstract

The present invention includes a Mytilus edulis cDNA having a nucleotide sequence that encodes for the Mytilus edulis foot protein-2 (Mefp-2), an example of a mollusk foot protein. Mefp-2 is an integral component of the blue mussels' adhesive protein complex, which allows the mussel to attach to objects underwater. The isolation, purification and sequencing of the Mefp-2 gene will allow researchers to produce Mefp-2 protein using genetic engineering techniques. The discovery of Mefp-2 gene sequences will also allow scientists to better understand how the blue mussel creates its waterproof adhesive protein complex.

Inventors:
;
Issue Date:
Research Org.:
Idaho National Lab. (INL), Idaho Falls, ID (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175639
Patent Number(s):
6995012
Application Number:
10/915,160
Assignee:
Battelle Energy Alliance, LLC (Idaho Falls, ID)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07H - SUGARS
DOE Contract Number:  
AC07-05ID14517
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Silverman, Heather G., and Roberto, Francisco F. Cloning and expression of recombinant adhesive protein MEFP-2 of the blue mussel, Mytilus edulis. United States: N. p., 2006. Web.
Silverman, Heather G., & Roberto, Francisco F. Cloning and expression of recombinant adhesive protein MEFP-2 of the blue mussel, Mytilus edulis. United States.
Silverman, Heather G., and Roberto, Francisco F. Tue . "Cloning and expression of recombinant adhesive protein MEFP-2 of the blue mussel, Mytilus edulis". United States. https://www.osti.gov/servlets/purl/1175639.
@article{osti_1175639,
title = {Cloning and expression of recombinant adhesive protein MEFP-2 of the blue mussel, Mytilus edulis},
author = {Silverman, Heather G. and Roberto, Francisco F.},
abstractNote = {The present invention includes a Mytilus edulis cDNA having a nucleotide sequence that encodes for the Mytilus edulis foot protein-2 (Mefp-2), an example of a mollusk foot protein. Mefp-2 is an integral component of the blue mussels' adhesive protein complex, which allows the mussel to attach to objects underwater. The isolation, purification and sequencing of the Mefp-2 gene will allow researchers to produce Mefp-2 protein using genetic engineering techniques. The discovery of Mefp-2 gene sequences will also allow scientists to better understand how the blue mussel creates its waterproof adhesive protein complex.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2006},
month = {2}
}

Patent:

Save / Share:

Works referenced in this record:

Adhesion and substrate choice in mussels and barnacles
journal, March 1985


Role of l -3,4-Dihydroxyphenylalanine in Mussel Adhesive Proteins
journal, June 1999


Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
journal, September 1997


Expression Sites of Two Byssal Protein Genes of Mytilus galloprovincialis
journal, April 1996


Minireview-Polyphenols and Oxidases in Substratum Adhesion by Marine Algae and Mussels
journal, February 1998


Mussel Adhesive Plaque Protein Gene Is a Novel Member of Epidermal Growth Factor-like Gene Family
journal, March 1995


Metal-Mediated Cross-Linking in the Generation of a Marine-Mussel Adhesive
journal, January 2004


A potential mediator of collagenous block copolymer gradients in mussel byssal threads
journal, September 1998


Applications and statistics for multiple high-scoring segments in molecular sequences.
journal, June 1993


Characterization of a Cystine-Rich Polyphenolic Protein Family from the Blue Mussel Mytilus edulis L
journal, August 1992


Polyphosphoprotein from the Adhesive Pads of Mytilus edulis
journal, March 2001


Hydroxyarginine-containing Polyphenolic Proteins in the Adhesive Plaques of the Marine Mussel Mytilus edulis
journal, August 1995


Mussel Adhesive Enhances the Immobilization of Human Chorionic Gonadotrophin to a Solid Support
journal, October 1996