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Title: Design of novel assays based on the newly found role of dystroglycan and alpha-dystroglycan proteolysis in tumor cell growth

Abstract

The invention provides method for assessing tumorigenicity of mammalian cells by assaying the proteolytic fragments of 120-130 kD alpha-dystroglycan in medium surrounding mammalian cells.

Inventors:
;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175602
Patent Number(s):
6982151
Application Number:
09/652,493
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC03-76SF0098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Bissell, Mina J., and Muschler, John L. Design of novel assays based on the newly found role of dystroglycan and alpha-dystroglycan proteolysis in tumor cell growth. United States: N. p., 2006. Web.
Bissell, Mina J., & Muschler, John L. Design of novel assays based on the newly found role of dystroglycan and alpha-dystroglycan proteolysis in tumor cell growth. United States.
Bissell, Mina J., and Muschler, John L. Tue . "Design of novel assays based on the newly found role of dystroglycan and alpha-dystroglycan proteolysis in tumor cell growth". United States. https://www.osti.gov/servlets/purl/1175602.
@article{osti_1175602,
title = {Design of novel assays based on the newly found role of dystroglycan and alpha-dystroglycan proteolysis in tumor cell growth},
author = {Bissell, Mina J. and Muschler, John L.},
abstractNote = {The invention provides method for assessing tumorigenicity of mammalian cells by assaying the proteolytic fragments of 120-130 kD alpha-dystroglycan in medium surrounding mammalian cells.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2006},
month = {1}
}

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Works referenced in this record:

A Role for Dystroglycan in Basement Membrane Assembly
journal, December 1998


Functional Rescue of the Sarcoglycan Complex in the BIO 14.6 Hamster Using δ-Sarcoglycan Gene Transfer
journal, May 1998


Value of Prostate-Specific Antigen as a Tumor Marker
journal, January 1993


Non-muscle alpha-dystroglycan is involved in epithelial development.
journal, July 1995


Another Anniversary for the War on Cancer
journal, March 1994


A Role of Dystroglycan in Schwannoma Cell Adhesion to Laminin
journal, May 1997


Differential expression of dystrophin, utrophin and dystrophin-associated proteins in peripheral nerve
journal, November 1993


Reduced expression of dystroglycan in breast and prostate cancer
journal, August 2001