Portable pathogen detection system
Abstract
A portable pathogen detection system that accomplishes on-site multiplex detection of targets in biological samples. The system includes: microbead specific reagents, incubation/mixing chambers, a disposable microbead capture substrate, and an optical measurement and decoding arrangement. The basis of this system is a highly flexible Liquid Array that utilizes optically encoded microbeads as the templates for biological assays. Target biological samples are optically labeled and captured on the microbeads, which are in turn captured on an ordered array or disordered array disposable capture substrate and then optically read.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States); Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1175389
- Patent Number(s):
- 6905885
- Application Number:
- 09/880,515
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Colston, Billy W., Everett, Matthew, Milanovich, Fred P., Brown, Steve B., Vendateswaran, Kodumudi, and Simon, Jonathan N. Portable pathogen detection system. United States: N. p., 2005.
Web.
Colston, Billy W., Everett, Matthew, Milanovich, Fred P., Brown, Steve B., Vendateswaran, Kodumudi, & Simon, Jonathan N. Portable pathogen detection system. United States.
Colston, Billy W., Everett, Matthew, Milanovich, Fred P., Brown, Steve B., Vendateswaran, Kodumudi, and Simon, Jonathan N. Tue .
"Portable pathogen detection system". United States. https://www.osti.gov/servlets/purl/1175389.
@article{osti_1175389,
title = {Portable pathogen detection system},
author = {Colston, Billy W. and Everett, Matthew and Milanovich, Fred P. and Brown, Steve B. and Vendateswaran, Kodumudi and Simon, Jonathan N.},
abstractNote = {A portable pathogen detection system that accomplishes on-site multiplex detection of targets in biological samples. The system includes: microbead specific reagents, incubation/mixing chambers, a disposable microbead capture substrate, and an optical measurement and decoding arrangement. The basis of this system is a highly flexible Liquid Array that utilizes optically encoded microbeads as the templates for biological assays. Target biological samples are optically labeled and captured on the microbeads, which are in turn captured on an ordered array or disordered array disposable capture substrate and then optically read.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {6}
}
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Works referenced in this record:
Light-directed, spatially addressable parallel chemical synthesis
journal, February 1991
- Fodor, S.; Read, J.; Pirrung, M.
- Science, Vol. 251, Issue 4995