Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples
Abstract
A method of detecting cancer using a laser biocavity having a semiconductor laser including a microchannel through which cells in fluid traverse, comprising determining the laser wavelength of the laser biocavity with only fluid in the microchannel; determining the wavelength shift of the biocavity when each cell passes through the microchannel; and determining the percentage of cells in G2 phase from the wavelength shift of the cells; wherein an increased percentage of G2 phase cells is an indication of cancer.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-CA), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1175330
- Patent Number(s):
- 6884624
- Assignee:
- Sandia Corporation
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC04-95AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Gourley, Paul L. Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples. United States: N. p., 2005.
Web.
Gourley, Paul L. Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples. United States.
Gourley, Paul L. Tue .
"Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples". United States. https://www.osti.gov/servlets/purl/1175330.
@article{osti_1175330,
title = {Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples},
author = {Gourley, Paul L.},
abstractNote = {A method of detecting cancer using a laser biocavity having a semiconductor laser including a microchannel through which cells in fluid traverse, comprising determining the laser wavelength of the laser biocavity with only fluid in the microchannel; determining the wavelength shift of the biocavity when each cell passes through the microchannel; and determining the percentage of cells in G2 phase from the wavelength shift of the cells; wherein an increased percentage of G2 phase cells is an indication of cancer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 26 00:00:00 EDT 2005},
month = {Tue Apr 26 00:00:00 EDT 2005}
}
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Works referenced in this record:
Semiconductor microlasers: A new approach to cell–structure analysis
journal, August 1996
- Gourley, P. L.
- Nature Medicine, Vol. 2, Issue 8
Surface-emitting semiconductor laser for intracavity spectroscopy and microscopy
conference, June 1995
- Meissner, Ken E.; Gourley, Paul L.; Brennan, Thomas M.
- Photonics West '95, SPIE Proceedings
MICROLASER-OPTICAL-MECHANICAL SYSTEMS FOR BIOMEDICINE: A biological microcavity laser for cell structure analysis
journal, January 1997
- Gourley, P. L.
- Optics and Photonics News, Vol. 8, Issue 4