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Title: Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples

Abstract

A method of detecting cancer using a laser biocavity having a semiconductor laser including a microchannel through which cells in fluid traverse, comprising determining the laser wavelength of the laser biocavity with only fluid in the microchannel; determining the wavelength shift of the biocavity when each cell passes through the microchannel; and determining the percentage of cells in G2 phase from the wavelength shift of the cells; wherein an increased percentage of G2 phase cells is an indication of cancer.

Inventors:
Issue Date:
Research Org.:
Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175330
Patent Number(s):
6884624
Assignee:
Sandia Corporation
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC04-95AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Gourley, Paul L. Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples. United States: N. p., 2005. Web.
Gourley, Paul L. Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples. United States.
Gourley, Paul L. Tue . "Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples". United States. https://www.osti.gov/servlets/purl/1175330.
@article{osti_1175330,
title = {Method for measuring the rate of cell reproduction by analysis of nanoliter cell samples},
author = {Gourley, Paul L.},
abstractNote = {A method of detecting cancer using a laser biocavity having a semiconductor laser including a microchannel through which cells in fluid traverse, comprising determining the laser wavelength of the laser biocavity with only fluid in the microchannel; determining the wavelength shift of the biocavity when each cell passes through the microchannel; and determining the percentage of cells in G2 phase from the wavelength shift of the cells; wherein an increased percentage of G2 phase cells is an indication of cancer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {4}
}

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Works referenced in this record:

Semiconductor microlasers: A new approach to cell–structure analysis
journal, August 1996


Surface-emitting semiconductor laser for intracavity spectroscopy and microscopy
conference, June 1995