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Title: Enhancement of NMR and MRI in the presence of hyperpolarized noble gases

Abstract

The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.

Inventors:
; ; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175127
Patent Number(s):
6818202
Application Number:
10/164,324
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
G - PHYSICS G01 - MEASURING G01R - MEASURING ELECTRIC VARIABLES
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY

Citation Formats

Pines, Alexander, Budinger, Thomas, Navon, Gil, Song, Yi-Qiao, Appelt, Stephan, Bifone, Angelo, Taylor, Rebecca, Goodson, Boyd, Seydoux, Roberto, Room, Toomas, and Pietrass, Tanja. Enhancement of NMR and MRI in the presence of hyperpolarized noble gases. United States: N. p., 2004. Web.
Pines, Alexander, Budinger, Thomas, Navon, Gil, Song, Yi-Qiao, Appelt, Stephan, Bifone, Angelo, Taylor, Rebecca, Goodson, Boyd, Seydoux, Roberto, Room, Toomas, & Pietrass, Tanja. Enhancement of NMR and MRI in the presence of hyperpolarized noble gases. United States.
Pines, Alexander, Budinger, Thomas, Navon, Gil, Song, Yi-Qiao, Appelt, Stephan, Bifone, Angelo, Taylor, Rebecca, Goodson, Boyd, Seydoux, Roberto, Room, Toomas, and Pietrass, Tanja. Tue . "Enhancement of NMR and MRI in the presence of hyperpolarized noble gases". United States. https://www.osti.gov/servlets/purl/1175127.
@article{osti_1175127,
title = {Enhancement of NMR and MRI in the presence of hyperpolarized noble gases},
author = {Pines, Alexander and Budinger, Thomas and Navon, Gil and Song, Yi-Qiao and Appelt, Stephan and Bifone, Angelo and Taylor, Rebecca and Goodson, Boyd and Seydoux, Roberto and Room, Toomas and Pietrass, Tanja},
abstractNote = {The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {11}
}

Patent:

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