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Title: Detection of biological molecules using chemical amplification and optical sensors

Abstract

Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.

Inventors:
;
Issue Date:
Research Org.:
MiniMed, Inc., Sylmar, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175079
Patent Number(s):
6804544
Application Number:
09/934,390
Assignee:
MiniMed, Inc. (Sylmar, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Van Antwerp, William Peter, and Mastrototaro, John Joseph. Detection of biological molecules using chemical amplification and optical sensors. United States: N. p., 2004. Web.
Van Antwerp, William Peter, & Mastrototaro, John Joseph. Detection of biological molecules using chemical amplification and optical sensors. United States.
Van Antwerp, William Peter, and Mastrototaro, John Joseph. Tue . "Detection of biological molecules using chemical amplification and optical sensors". United States. https://www.osti.gov/servlets/purl/1175079.
@article{osti_1175079,
title = {Detection of biological molecules using chemical amplification and optical sensors},
author = {Van Antwerp, William Peter and Mastrototaro, John Joseph},
abstractNote = {Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {10}
}

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Works referenced in this record:

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