Title: Polymer arrays from the combinatorial synthesis of novel materials

Abstract

Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc. Once prepared, these materials can be screened for useful properties including, for example, electrical, thermal, mechanical, morphological, optical, magnetic, chemical, or other properties. Thus, the present invention provides methods for the parallel synthesis and analysis of novel materials having useful properties.

Inventors:

Schultz, Peter G.; Xiang, Xiao-Dong; Goldwasser, Isy; Briceno, Gabriel; Sun, Xiao-Dong

Issue Date:

2004-09-21

Research Org.:

Univ. of California, Oakland, CA (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1175047

Patent Number(s):

6794052

Application Number:

10/226,485

Assignee:

University Of California, The Regents Of

Patent Classifications (CPCs):

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY

B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY

B01J19/0046 - {Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides
B01J2219/00313 - the reactor vessels being formed by arrays of wells in blocks
B01J2219/00317 - Microwell devices, i.e. having large numbers of wells
B01J2219/00378 - Piezo-electric or ink jet dispensers
B01J2219/0043 - for direct application of reagents, e.g. through openings in a shutter
B01J2219/00432 - Photolithographic masks
B01J2219/00436 - Maskless processes
B01J2219/00441 - using lasers
B01J2219/00443 - Thin film deposition
B01J2219/00475 - Sheets
B01J2219/005 - Beads
B01J2219/00511 - Walls of reactor vessels
B01J2219/00515 - in the shape of strings
B01J2219/0052 - in the shape of elongated tubes
B01J2219/00527 - Sheets
B01J2219/00531 - essentially square
B01J2219/00533 - essentially rectangular
B01J2219/00536 - in the shape of disks
B01J2219/0054 - Means for coding or tagging the apparatus or the reagents
B01J2219/00585 - Parallel processes
B01J2219/0059 - Sequential processes
B01J2219/00592 - Split-and-pool, mix-and-divide processes
B01J2219/00596 - Solid-phase processes
B01J2219/00605 - the compounds being directly bound or immobilised to solid supports
B01J2219/0061 - The surface being organic
B01J2219/00612 - the surface being inorganic
B01J2219/00619 - using hydrophilic or hydrophobic regions
B01J2219/00621 - by physical means, e.g. trenches, raised areas
B01J2219/00626 - Covalent
B01J2219/00628 - Ionic
B01J2219/0063 - Other, e.g. van der Waals forces, hydrogen bonding
B01J2219/00635 - by reactive plasma treatment
B01J2219/00637 - by coating it with another layer
B01J2219/00644 - the porous medium being present in discrete locations, e.g. gel pads
B01J2219/00646 - the compounds being bound to beads immobilised on the solid supports
B01J2219/00648 - by the use of solid beads
B01J2219/00659 - Two-dimensional arrays
B01J2219/00689 - using computers
B01J2219/00691 - using robots
B01J2219/00711 - Light-directed synthesis
B01J2219/0072 - Organic compounds
B01J2219/00722 - Nucleotides
B01J2219/00736 - Non-biologic macromolecules, e.g. polymeric compounds
B01J2219/00745 - Inorganic compounds
B01J2219/00747 - Catalysts
B01J2219/00752 - Alloys
B01J2219/00754 - Metal oxides

B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES

B82Y25/00 - Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
B82Y30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

C - CHEMISTRY C01 - INORGANIC CHEMISTRY C01G - COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F

C01G51/006 - {Compounds containing, besides cobalt, two or more other elements, with the exception of oxygen or hydrogen
C01G51/68 - {containing rare earth, e.g. La0.3Sr0.7CoO3}

C - CHEMISTRY C01 - INORGANIC CHEMISTRY C01P - INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS

C01P2002/34 - perovskite-type
C01P2002/52 - containing elements as dopants
C01P2002/72 - by d-values or two theta-values, e.g. as X-ray diagram
C01P2004/84 - one phase coated with the other
C01P2006/40 - Electric properties
C01P2006/42 - Magnetic properties

C - CHEMISTRY C04 - CEMENTS C04B - LIME, MAGNESIA

C04B2235/3206 - Magnesium oxides or oxide-forming salts thereof
C04B2235/3208 - Calcium oxide or oxide-forming salts thereof, e.g. lime
C04B2235/3213 - Strontium oxides or oxide-forming salts thereof
C04B2235/3215 - Barium oxides or oxide-forming salts thereof
C04B2235/3224 - Rare earth oxide or oxide forming salts thereof, e.g. scandium oxide
C04B2235/3225 - Yttrium oxide or oxide-forming salts thereof
C04B2235/3227 - Lanthanum oxide or oxide-forming salts thereof
C04B2235/3262 - Manganese oxides, manganates, rhenium oxides or oxide-forming salts thereof, e.g. MnO
C04B2235/327 - Iron group oxides, their mixed metal oxides, or oxide-forming salts thereof
C04B2235/3275 - Cobalt oxides, cobaltates or cobaltites or oxide forming salts thereof, e.g. bismuth cobaltate, zinc cobaltite
C04B2235/3284 - Zinc oxides, zincates, cadmium oxides, cadmiates, mercury oxides, mercurates or oxide forming salts thereof
C04B2235/3286 - Gallium oxides, gallates, indium oxides, indates, thallium oxides, thallates or oxide forming salts thereof, e.g. zinc gallate
C04B2235/3296 - Lead oxides, plumbates or oxide forming salts thereof, e.g. silver plumbate
C04B2235/3298 - Bismuth oxides, bismuthates or oxide forming salts thereof, e.g. zinc bismuthate
C04B2235/3418 - Silicon oxide, silicic acids, or oxide forming salts thereof, e.g. silica sol, fused silica, silica fume, cristobalite, quartz or flint
C04B2235/3463 - Alumino-silicates other than clay, e.g. mullite
C04B2235/656 - characterised by specific heating conditions during heat treatment
C04B2235/761 - Unit-cell parameters, e.g. lattice constants
C04B2235/762 - Cubic symmetry, e.g. beta-SiC
C04B2235/768 - Perovskite structure ABO3
C04B2235/96 - Properties of ceramic products, e.g. mechanical properties such as strength, toughness, wear resistance
C04B35/01 - based on oxide ceramics
C04B35/16 - based on silicates other than clay {
C04B35/4508 - {Type 1-2-3}
C04B35/4521 - {containing bismuth oxide}
C04B35/4525 - {also containing lead oxide}
C04B35/62218 - {obtaining ceramic films, e.g. by using temporary supports}

C - CHEMISTRY C23 - COATING METALLIC MATERIAL C23C - COATING METALLIC MATERIAL

C23C14/042 - {using masks}
C23C14/087 - {of copper or solid solutions thereof}
C23C16/042 - {using masks}

C - CHEMISTRY C40 - COMBINATORIAL TECHNOLOGY C40B - COMBINATORIAL CHEMISTRY

C40B30/08 - by measuring catalytic activity
C40B40/14 - Libraries containing macromolecular compounds and not covered by groups C40B40/06 - C40B40/12
C40B40/18 - Libraries containing only inorganic compounds or inorganic materials
C40B60/08 - Integrated apparatus specially adapted for both creating and screening libraries
C40B60/14 - for creating libraries
C40B70/00 - Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
C40B80/00 - Linkers or spacers specially adapted for combinatorial chemistry or libraries, e.g. traceless linkers or safety-catch linkers

G - PHYSICS G01 - MEASURING G01R - MEASURING ELECTRIC VARIABLES

G01R33/16 - Measuring susceptibility {

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01F - MAGNETS

H01F1/401 - {diluted}
H01F1/407 - {Diluted non-magnetic ions in a magnetic cation-sublattice, e.g. perovskites, La1-x
H01F10/007 - {ultrathin or granular films
H01F10/193 - Magnetic semiconductor compounds {
H01F10/1933 - {Perovskites}
H01F41/18 - by cathode sputtering
H01F41/34 - in patterns, e.g. by lithography

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

Y10T428/24479 - including variation in thickness
Y10T428/24612 - Composite web or sheet
Y10T428/2462 - with partial filling of valleys on outer surface
Y10T428/31 - Surface property or characteristic of web, sheet or block
Y10T428/31645 - Next to addition polymer from unsaturated monomers
Y10T428/31855 - Of addition polymer from unsaturated monomers
Y10T428/31931 - Polyene monomer-containing
Y10T436/25 - including sample preparation
Y10T436/2525 - Stabilizing or preserving
Y10T436/255 - including use of a solid sorbent, semipermeable membrane, or liquid extraction
Y10T436/25875 - Gaseous sample or with change of physical state

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DOE Contract Number:  

AC03-76SF00098

Resource Type:

Patent

Country of Publication:

United States

Language:

English

Subject:

36 MATERIALS SCIENCE