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Title: Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream

Abstract

A microfluidic device for forming and/or dispensing minute volume segments of a material is described. In accordance with one aspect of the present invention, a microfluidic device and method is provided for spatially confining the material in a focusing element. The device is also capable of segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.

Inventors:
;
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175027
Patent Number(s):
6790328
Application Number:
09/759,590
Assignee:
UT-Battelle, LLC (TN)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC05-00OR22725
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING

Citation Formats

Jacobson, Stephen C., and Ramsey, J. Michael. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream. United States: N. p., 2004. Web.
Jacobson, Stephen C., & Ramsey, J. Michael. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream. United States.
Jacobson, Stephen C., and Ramsey, J. Michael. Tue . "Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream". United States. https://www.osti.gov/servlets/purl/1175027.
@article{osti_1175027,
title = {Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream},
author = {Jacobson, Stephen C. and Ramsey, J. Michael},
abstractNote = {A microfluidic device for forming and/or dispensing minute volume segments of a material is described. In accordance with one aspect of the present invention, a microfluidic device and method is provided for spatially confining the material in a focusing element. The device is also capable of segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {9}
}

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Works referenced in this record:

Electrokinetic Flow in a Narrow Cylindrical Capillary
journal, November 1965


Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip
journal, August 1993


Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip
journal, August 1993


Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)
journal, October 1998