High mass throughput particle generation using multiple nozzle spraying
Abstract
Spraying apparatus and methods that employ multiple nozzle structures for producing multiple sprays of particles, e.g., nanoparticles, for various applications, e.g., pharmaceuticals, are provided. For example, an electrospray dispensing device may include a plurality of nozzle structures, wherein each nozzle structure is separated from adjacent nozzle structures by an internozzle distance. Sprays of particles are established from the nozzle structures by creating a nonuniform electrical field between the nozzle structures and an electrode electrically isolated therefrom.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Minnesota, Minneapolis, MN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174954
- Patent Number(s):
- 6764720
- Application Number:
- 09/858,865
- Assignee:
- Regents of the University of Minnesota (Minneapolis, MN)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61F - FILTERS IMPLANTABLE INTO BLOOD VESSELS
B - PERFORMING OPERATIONS B05 - SPRAYING OR ATOMISING IN GENERAL B05B - SPRAYING APPARATUS
- DOE Contract Number:
- FG02-98ER14909
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING
Citation Formats
Pui, David Y.H., and Chen, Da-Ren. High mass throughput particle generation using multiple nozzle spraying. United States: N. p., 2004.
Web.
Pui, David Y.H., & Chen, Da-Ren. High mass throughput particle generation using multiple nozzle spraying. United States.
Pui, David Y.H., and Chen, Da-Ren. Tue .
"High mass throughput particle generation using multiple nozzle spraying". United States. https://www.osti.gov/servlets/purl/1174954.
@article{osti_1174954,
title = {High mass throughput particle generation using multiple nozzle spraying},
author = {Pui, David Y.H. and Chen, Da-Ren},
abstractNote = {Spraying apparatus and methods that employ multiple nozzle structures for producing multiple sprays of particles, e.g., nanoparticles, for various applications, e.g., pharmaceuticals, are provided. For example, an electrospray dispensing device may include a plurality of nozzle structures, wherein each nozzle structure is separated from adjacent nozzle structures by an internozzle distance. Sprays of particles are established from the nozzle structures by creating a nonuniform electrical field between the nozzle structures and an electrode electrically isolated therefrom.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {7}
}
Works referenced in this record:
Unipolar Diffusion Charging of Ultrafine Aerosols
journal, January 1988
- Pui, D. Y. H.; Fruin, S.; McMurry, P. H.
- Aerosol Science and Technology, Vol. 8, Issue 2
Performance of a unipolar “square wave” diffusion charger with variable nt-product
journal, June 1994
- Büscher, P.; Schmidt-Ott, A.; Wiedensohler, A.
- Journal of Aerosol Science, Vol. 25, Issue 4, p. 651-663
Free electron charging of ultrafine aerosol particles
journal, October 1992
- Romay, Francisco J.; Pui, David Y. H.
- Journal of Aerosol Science, Vol. 23, Issue 7, p. 679-692
Unipolar and bipolar diffusion charging of ultrafine aerosol particles
journal, January 1985
- Adachi, M.; Kousaka, Y.; Okuyama, K.
- Journal of Aerosol Science, Vol. 16, Issue 2, p. 109-123
Nanometer particles: A new frontier for multidisciplinary research
journal, June 1997
- Pui, David Y. H.; Chen, Da-Ren
- Journal of Aerosol Science, Vol. 28, Issue 4, p. 539-544
New microfluidic technologies to generate respirable aerosols for medical applications
journal, September 1999
- Gan˜án-Calvo, Alfonso M.
- Journal of Aerosol Science, Vol. 30
On the Combination Coefficient of Positive Ions with Ultrafine Neutral Particles in the Transition and Free-Molecule Regimes
journal, January 1992
- Romay, Francisco J.; Pui, David Y. H.
- Aerosol Science and Technology, Vol. 17, Issue 2
A novel unipolar charger for ultrafine aerosol particles with minimal particle losses
journal, June 1994
- Wiedensohler, A.; Büscher, P.; Hansson, H.-C.
- Journal of Aerosol Science, Vol. 25, Issue 4, p. 639-649
Advances in alternative DNA delivery techniques
journal, January 1995
- Songstad, D. D.; Somers, D. A.; Griesbach, R. J.
- Plant Cell, Tissue and Organ Culture, Vol. 40, Issue 1
Unipolar Diffusion Charging of Aerosol Particles at Low Pressure
journal, January 1991
- Romay, Francisco J.; Pui, David Y. H.; Adachi, Motoaki
- Aerosol Science and Technology, Vol. 15, Issue 1
Scale‐up of electrospray atomization using linear arrays of Taylor cones
journal, March 1993
- Rulison, Aaron J.; Flagan, Richard C.
- Review of Scientific Instruments, Vol. 64, Issue 3
Design and evaluation of a nanometer aerosol differential mobility analyzer (Nano-DMA)
journal, June 1998
- Chen, D.-R.; Pui, D. Y. H.; Hummes, D.
- Journal of Aerosol Science, Vol. 29, Issue 5-6, p. 497-509
Generation of Steady Liquid Microthreads and Micron-Sized Monodisperse Sprays in Gas Streams
journal, January 1998
- Gañán-Calvo, Alfonso M.
- Physical Review Letters, Vol. 80, Issue 2
The Nonequilibrium Character of the Aerosol Charge Distributions Produced by Neutralizes
journal, January 1990
- Hoppel, W. A.; Frick, G. M.
- Aerosol Science and Technology, Vol. 12, Issue 3
On unipolar diffusion charging of aerosols in the continuum regime
journal, January 1977
- Liu, Benjamin Y. H.; Pui, David Y. H.
- Journal of Colloid and Interface Science, Vol. 58, Issue 1, p. 142-149
Electrospraying of conducting liquids for monodisperse aerosol generation in the 4 nm to 1.8 μm diameter range
journal, September 1995
- Chen, Da-Ren; Pui, David Y. H.; Kaufman, Stanley L.
- Journal of Aerosol Science, Vol. 26, Issue 6, p. 963-977
Experimental Investigation of Scaling Laws for Electrospraying: Dielectric Constant Effect
journal, September 1997
- Chen, Da-Ren; Pui, David Y. H.
- Aerosol Science and Technology, Vol. 27, Issue 3