High throughput microcantilever detector
Abstract
In an improved uncoated microcantilever detector, the sample sites are placed on a separate semi-conducting substrate and the microcantilever element detects and measures the changes before and after a chemical interaction or hybridization of the sites by sensing differences of phase angle between an alternating voltage applied to the microcantilever element and vibration of the microcantilever element. In another embodiment of the invention, multiple sample sites are on a sample array wherein an array of microcantilever elements detect and measure the change before and after chemical interactions or hybridizations of the sample sites.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174950
- Patent Number(s):
- 6763705
- Application Number:
- 10/462,249
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Thundat, Thomas G., Ferrell, Thomas L., Hansen, Karolyn M., and Tian, Fang. High throughput microcantilever detector. United States: N. p., 2004.
Web.
Thundat, Thomas G., Ferrell, Thomas L., Hansen, Karolyn M., & Tian, Fang. High throughput microcantilever detector. United States.
Thundat, Thomas G., Ferrell, Thomas L., Hansen, Karolyn M., and Tian, Fang. Tue .
"High throughput microcantilever detector". United States. https://www.osti.gov/servlets/purl/1174950.
@article{osti_1174950,
title = {High throughput microcantilever detector},
author = {Thundat, Thomas G. and Ferrell, Thomas L. and Hansen, Karolyn M. and Tian, Fang},
abstractNote = {In an improved uncoated microcantilever detector, the sample sites are placed on a separate semi-conducting substrate and the microcantilever element detects and measures the changes before and after a chemical interaction or hybridization of the sites by sensing differences of phase angle between an alternating voltage applied to the microcantilever element and vibration of the microcantilever element. In another embodiment of the invention, multiple sample sites are on a sample array wherein an array of microcantilever elements detect and measure the change before and after chemical interactions or hybridizations of the sample sites.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {7}
}
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