Self assembling proteins
Abstract
Novel fusion proteins capable of self-assembling into regular structures, as well as nucleic acids encoding the same, are provided. The subject fusion proteins comprise at least two oligomerization domains rigidly linked together, e.g. through an alpha helical linking group. Also provided are regular structures comprising a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of a variety of nanostructures, where such structures include: cages, shells, double-layer rings, two-dimensional layers, three-dimensional crystals, filaments, and tubes.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174921
- Patent Number(s):
- 6756039
- Application Number:
- 09/564,710
- Assignee:
- University Of California, The Regents Of
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- FGO3-87ER60615
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Yeates, Todd O., Padilla, Jennifer, and Colovos, Chris. Self assembling proteins. United States: N. p., 2004.
Web.
Yeates, Todd O., Padilla, Jennifer, & Colovos, Chris. Self assembling proteins. United States.
Yeates, Todd O., Padilla, Jennifer, and Colovos, Chris. Tue .
"Self assembling proteins". United States. https://www.osti.gov/servlets/purl/1174921.
@article{osti_1174921,
title = {Self assembling proteins},
author = {Yeates, Todd O. and Padilla, Jennifer and Colovos, Chris},
abstractNote = {Novel fusion proteins capable of self-assembling into regular structures, as well as nucleic acids encoding the same, are provided. The subject fusion proteins comprise at least two oligomerization domains rigidly linked together, e.g. through an alpha helical linking group. Also provided are regular structures comprising a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of a variety of nanostructures, where such structures include: cages, shells, double-layer rings, two-dimensional layers, three-dimensional crystals, filaments, and tubes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 29 00:00:00 EDT 2004},
month = {Tue Jun 29 00:00:00 EDT 2004}
}
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