Self assembling proteins
Abstract
Novel fusion proteins capable of self-assembling into regular structures, as well as nucleic acids encoding the same, are provided. The subject fusion proteins comprise at least two oligomerization domains rigidly linked together, e.g. through an alpha helical linking group. Also provided are regular structures comprising a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of a variety of nanostructures, where such structures include: cages, shells, double-layer rings, two-dimensional layers, three-dimensional crystals, filaments, and tubes.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174921
- Patent Number(s):
- 6756039
- Application Number:
- 09/564,710
- Assignee:
- University Of California, The Regents Of
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- FGO3-87ER60615
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Yeates, Todd O., Padilla, Jennifer, and Colovos, Chris. Self assembling proteins. United States: N. p., 2004.
Web.
Yeates, Todd O., Padilla, Jennifer, & Colovos, Chris. Self assembling proteins. United States.
Yeates, Todd O., Padilla, Jennifer, and Colovos, Chris. Tue .
"Self assembling proteins". United States. https://www.osti.gov/servlets/purl/1174921.
@article{osti_1174921,
title = {Self assembling proteins},
author = {Yeates, Todd O. and Padilla, Jennifer and Colovos, Chris},
abstractNote = {Novel fusion proteins capable of self-assembling into regular structures, as well as nucleic acids encoding the same, are provided. The subject fusion proteins comprise at least two oligomerization domains rigidly linked together, e.g. through an alpha helical linking group. Also provided are regular structures comprising a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of a variety of nanostructures, where such structures include: cages, shells, double-layer rings, two-dimensional layers, three-dimensional crystals, filaments, and tubes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {6}
}
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Works referenced in this record:
A Chemically Functionalizable Nanoporous Material [Cu3(TMA)2(H2O)3]n
journal, February 1999
- Chui, Stephen S.-Y.; Lo, Samuel M.-F.; Charmant, Jonathan P. H.
- Science, Vol. 283, Issue 5405, p. 1148-1150
Why protein crystals favour some space-groups over others
journal, December 1995
- Wukovitz, Stephanie W.; Yeates, Todd O.
- Nature Structural & Molecular Biology, Vol. 2, Issue 12
Fullerenes and carbon nanotubes
journal, April 1996
- Rao, Cnr; Sen, Rahul; Govindaraj, A.
- Current Opinion in Solid State and Materials Science, Vol. 1, Issue 2
Supertetrahedral Sulfide Crystals with Giant Cavities and Channels
journal, February 1999
- Li, Hailian; Laine, Aaron; O'Keefe, M.
- Science, Vol. 283, Issue 5405, p. 1145-1147
Nanometre-size tubes of carbon
journal, October 1997
- Ajayan, P. M.; Ebbesen, T. W.
- Reports on Progress in Physics, Vol. 60, Issue 10
DNA engineering and its application to nanotechnology
journal, November 1999
- Seeman, Nadrian C.
- Trends in Biotechnology, Vol. 17, Issue 11
Nanocrystal Superlattices
journal, October 1998
- Collier, C. P.; Vossmeyer, T.; Heath, J. R.
- Annual Review of Physical Chemistry, Vol. 49, Issue 1
Self-assembling organic nanotubes based on a cyclic peptide architecture
journal, December 1993
- Ghadiri, M. Reza; Granja, Juan R.; Milligan, Ronald A.
- Nature, Vol. 366, Issue 6453
The stability of the fullerenes Cn, with n = 24, 28, 32, 36, 50, 60 and 70
journal, October 1987
- Kroto, H. W.
- Nature, Vol. 329, Issue 6139
Helical microtubules of graphitic carbon
journal, November 1991
- Iijima, Sumio
- Nature, Vol. 354, Issue 6348
Self-organizing molecular networks
journal, May 1998
- Stange, P.; Zanette, D.; Mikhailov, A.
- Biophysical Chemistry, Vol. 72, Issue 1-2