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Title: Method to produce succinic acid from raw hydrolysates

Abstract

A method for producing succinic acid from industrial-grade hydrolysates is provided, comprising supplying an organism that contains mutations for the genes ptsG, pflB, and ldhA, allowing said organism to accumulate biomass, and allowing said organism to metabolize the hydrolysate. Also provided is a bacteria mutant characterized in that it produces succinic acid from substrate contained in industrial-grade hydrolysate in a ratio of between 0.6:1 and 1.3:1 succinic acid to substrate.

Inventors:
; ;
Issue Date:
Research Org.:
Univ. of Chicago, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174873
Patent Number(s):
6743610
Application Number:
09/823,949
Assignee:
University Of Chicago
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
W-31-109-ENG-38
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Donnelly, Mark I., Sanville-Millard, Cynthia Y., and Nghiem, Nhuan Phu. Method to produce succinic acid from raw hydrolysates. United States: N. p., 2004. Web.
Donnelly, Mark I., Sanville-Millard, Cynthia Y., & Nghiem, Nhuan Phu. Method to produce succinic acid from raw hydrolysates. United States.
Donnelly, Mark I., Sanville-Millard, Cynthia Y., and Nghiem, Nhuan Phu. Tue . "Method to produce succinic acid from raw hydrolysates". United States. https://www.osti.gov/servlets/purl/1174873.
@article{osti_1174873,
title = {Method to produce succinic acid from raw hydrolysates},
author = {Donnelly, Mark I. and Sanville-Millard, Cynthia Y. and Nghiem, Nhuan Phu},
abstractNote = {A method for producing succinic acid from industrial-grade hydrolysates is provided, comprising supplying an organism that contains mutations for the genes ptsG, pflB, and ldhA, allowing said organism to accumulate biomass, and allowing said organism to metabolize the hydrolysate. Also provided is a bacteria mutant characterized in that it produces succinic acid from substrate contained in industrial-grade hydrolysate in a ratio of between 0.6:1 and 1.3:1 succinic acid to substrate.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {6}
}