Multifunctional and multispectral biosensor devices and methods of use
Abstract
An integrated biosensor system for the simultaneously detection of a plurality of different types of targets includes at least one sampling platform, the sampling platform including a plurality of receptors for binding to the targets. The plurality of receptors include at least one protein receptor and at least one nucleic acid receptor. At least one excitation source of electromagnetic radiation at a first frequency is provided for irradiating the receptors, wherein electromagnetic radiation at a second frequency different from the first frequency is emitted in response to irradiating when at least one of the different types of targets are bound to the receptor probes. An integrated circuit detector system having a plurality of detection channels is also provided for detecting electromagnetic radiation at said second frequency, the detection channels each including at least one detector.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174872
- Patent Number(s):
- 6743581
- Application Number:
- 09/890,047
- Assignee:
- UT-Battelle, LC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC05-96OR22464
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Vo-Dinh, Tuan. Multifunctional and multispectral biosensor devices and methods of use. United States: N. p., 2004.
Web.
Vo-Dinh, Tuan. Multifunctional and multispectral biosensor devices and methods of use. United States.
Vo-Dinh, Tuan. Tue .
"Multifunctional and multispectral biosensor devices and methods of use". United States. https://www.osti.gov/servlets/purl/1174872.
@article{osti_1174872,
title = {Multifunctional and multispectral biosensor devices and methods of use},
author = {Vo-Dinh, Tuan},
abstractNote = {An integrated biosensor system for the simultaneously detection of a plurality of different types of targets includes at least one sampling platform, the sampling platform including a plurality of receptors for binding to the targets. The plurality of receptors include at least one protein receptor and at least one nucleic acid receptor. At least one excitation source of electromagnetic radiation at a first frequency is provided for irradiating the receptors, wherein electromagnetic radiation at a second frequency different from the first frequency is emitted in response to irradiating when at least one of the different types of targets are bound to the receptor probes. An integrated circuit detector system having a plurality of detection channels is also provided for detecting electromagnetic radiation at said second frequency, the detection channels each including at least one detector.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 01 00:00:00 EDT 2004},
month = {Tue Jun 01 00:00:00 EDT 2004}
}
Works referenced in this record:
PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules
journal, October 1993
- Egholm, Michael; Buchardt, Ole; Christensen, Leif
- Nature, Vol. 365, Issue 6446