Method for preparing high specific activity 177Lu
Abstract
A method of separating lutetium from a solution containing Lu and Yb, particularly reactor-produced .sup.177 Lu and .sup.177 Yb, includes the steps of: providing a chromatographic separation apparatus containing LN resin; loading the apparatus with a solution containing Lu and Yb; and eluting the apparatus to chromatographically separate the Lu and the Yb in order to produce high-specific-activity .sup.177 Yb.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174799
- Patent Number(s):
- 6716353
- Application Number:
- 10/283,608
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Mirzadeh, Saed, Du, Miting, Beets, Arnold L., and Knapp, Jr., Furn F. Method for preparing high specific activity 177Lu. United States: N. p., 2004.
Web.
Mirzadeh, Saed, Du, Miting, Beets, Arnold L., & Knapp, Jr., Furn F. Method for preparing high specific activity 177Lu. United States.
Mirzadeh, Saed, Du, Miting, Beets, Arnold L., and Knapp, Jr., Furn F. Tue .
"Method for preparing high specific activity 177Lu". United States. https://www.osti.gov/servlets/purl/1174799.
@article{osti_1174799,
title = {Method for preparing high specific activity 177Lu},
author = {Mirzadeh, Saed and Du, Miting and Beets, Arnold L. and Knapp, Jr., Furn F.},
abstractNote = {A method of separating lutetium from a solution containing Lu and Yb, particularly reactor-produced .sup.177 Lu and .sup.177 Yb, includes the steps of: providing a chromatographic separation apparatus containing LN resin; loading the apparatus with a solution containing Lu and Yb; and eluting the apparatus to chromatographically separate the Lu and the Yb in order to produce high-specific-activity .sup.177 Yb.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 06 00:00:00 EDT 2004},
month = {Tue Apr 06 00:00:00 EDT 2004}
}
Works referenced in this record:
Radiochemical separation of no-carrier-added as produced via the process
journal, September 2000
- Lebedev, Nikolai A.; Novgorodov, Alexander F.; Misiak, Riscard
- Applied Radiation and Isotopes, Vol. 53, Issue 3
90 Y and 177 Lu Labeling of a DOTA-Conjugated Vitronectin Receptor Antagonist Useful for Tumor Therapy
journal, July 2001
- Liu, Shuang; Cheung, Eric; Ziegler, Marisa C.
- Bioconjugate Chemistry, Vol. 12, Issue 4