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Title: Compact electrochemical sensor system and method for field testing for metals in saliva or other fluids

Abstract

Microanalytical systems based on a microfluidics/electrochemical detection scheme are described. Individual modules, such as microfabricated piezoelectrically actuated pumps and a microelectrochemical cell were integrated onto portable platforms. This allowed rapid change-out and repair of individual components by incorporating "plug and play" concepts now standard in PC's. Different integration schemes were used for construction of the microanalytical systems based on microfluidics/electrochemical detection. In one scheme, all individual modules were integrated in the surface of the standard microfluidic platform based on a plug-and-play design. Microelectrochemical flow cell which integrated three electrodes based on a wall-jet design was fabricated on polymer substrate. The microelectrochemical flow cell was then plugged directly into the microfluidic platform. Another integration scheme was based on a multilayer lamination method utilizing stacking modules with different functionality to achieve a compact microanalytical device. Application of the microanalytical system for detection of lead in, for example, river water and saliva samples using stripping voltammetry is described.

Inventors:
; ; ;
Issue Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174745
Patent Number(s):
6699384
Application Number:
09/667,034
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01F - MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 47 OTHER INSTRUMENTATION

Citation Formats

Lin, Yuehe, Bennett, Wendy D., Timchalk, Charles, and Thrall, Karla D. Compact electrochemical sensor system and method for field testing for metals in saliva or other fluids. United States: N. p., 2004. Web.
Lin, Yuehe, Bennett, Wendy D., Timchalk, Charles, & Thrall, Karla D. Compact electrochemical sensor system and method for field testing for metals in saliva or other fluids. United States.
Lin, Yuehe, Bennett, Wendy D., Timchalk, Charles, and Thrall, Karla D. Tue . "Compact electrochemical sensor system and method for field testing for metals in saliva or other fluids". United States. https://www.osti.gov/servlets/purl/1174745.
@article{osti_1174745,
title = {Compact electrochemical sensor system and method for field testing for metals in saliva or other fluids},
author = {Lin, Yuehe and Bennett, Wendy D. and Timchalk, Charles and Thrall, Karla D.},
abstractNote = {Microanalytical systems based on a microfluidics/electrochemical detection scheme are described. Individual modules, such as microfabricated piezoelectrically actuated pumps and a microelectrochemical cell were integrated onto portable platforms. This allowed rapid change-out and repair of individual components by incorporating "plug and play" concepts now standard in PC's. Different integration schemes were used for construction of the microanalytical systems based on microfluidics/electrochemical detection. In one scheme, all individual modules were integrated in the surface of the standard microfluidic platform based on a plug-and-play design. Microelectrochemical flow cell which integrated three electrodes based on a wall-jet design was fabricated on polymer substrate. The microelectrochemical flow cell was then plugged directly into the microfluidic platform. Another integration scheme was based on a multilayer lamination method utilizing stacking modules with different functionality to achieve a compact microanalytical device. Application of the microanalytical system for detection of lead in, for example, river water and saliva samples using stripping voltammetry is described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {3}
}

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Works referenced in this record:

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journal, September 1987


Determination of Lead in Bonemeal by Differential Pulse Anodic Stripping Voltammetry Using a Hydrochloric Acid Solubilization
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