Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels
Abstract
A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either ionic current flow or the transport of gas species, while inhibiting the bulk flow of material. The use of bridging membranes in accordance with this invention is applicable to a variety of processes, including electrokinetically induced pressure flow in a region of a microchannel that is not influenced by an electric field, sample concentration enhancement and injection, as well as improving the analysis of materials where it is desired to eliminate electrophoretic bias. Other applications of the bridging membranes according to this invention include the separation of species from a sample material, valving of fluids in a microchannel network, mixing of different materials in a microchannel, and the pumping of fluids.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174708
- Patent Number(s):
- 6685809
- Application Number:
- 09/244,914
- Assignee:
- UT-Battelle, LLC (Wilmington, DE)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- DOE Contract Number:
- AC05-96OR22464
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 36 MATERIALS SCIENCE
Citation Formats
Jacobson, Stephen C., Ramsey, J. Michael, Culbertson, Christopher T., Whitten, William B., and Foote, Robert S. Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels. United States: N. p., 2004.
Web.
Jacobson, Stephen C., Ramsey, J. Michael, Culbertson, Christopher T., Whitten, William B., & Foote, Robert S. Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels. United States.
Jacobson, Stephen C., Ramsey, J. Michael, Culbertson, Christopher T., Whitten, William B., and Foote, Robert S. Tue .
"Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels". United States. https://www.osti.gov/servlets/purl/1174708.
@article{osti_1174708,
title = {Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels},
author = {Jacobson, Stephen C. and Ramsey, J. Michael and Culbertson, Christopher T. and Whitten, William B. and Foote, Robert S.},
abstractNote = {A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either ionic current flow or the transport of gas species, while inhibiting the bulk flow of material. The use of bridging membranes in accordance with this invention is applicable to a variety of processes, including electrokinetically induced pressure flow in a region of a microchannel that is not influenced by an electric field, sample concentration enhancement and injection, as well as improving the analysis of materials where it is desired to eliminate electrophoretic bias. Other applications of the bridging membranes according to this invention include the separation of species from a sample material, valving of fluids in a microchannel network, mixing of different materials in a microchannel, and the pumping of fluids.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 03 00:00:00 EST 2004},
month = {Tue Feb 03 00:00:00 EST 2004}
}
Works referenced in this record:
Electrokinetic Flow in a Narrow Cylindrical Capillary
journal, November 1965
- Rice, C. L.; Whitehead, R.
- The Journal of Physical Chemistry, Vol. 69, Issue 11
Development and analytical performance of tubular polymer membrane electrode-based carbon dioxide catheters
journal, April 1986
- Opdycke, Walter N.; Meyerhoff, M. E.
- Analytical Chemistry, Vol. 58, Issue 4
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)
journal, October 1998
- Duffy, David C.; McDonald, J. Cooper; Schueller, Olivier J. A.
- Analytical Chemistry, Vol. 70, Issue 23, p. 4974-4984