Methods for production of proteins in host cells
Abstract
The present invention provides methods for the production of proteins, particularly toxic proteins, in host cells. The invention provides methods which use a fusion protein comprising a chaperonin binding domain in host cells induced or regulated to have increased levels of chaperonin which binds the chaperonin binding domain.
- Inventors:
- Issue Date:
- Research Org.:
- Genecor International, Inc., Rochester, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174681
- Patent Number(s):
- 6677139
- Application Number:
- 09/470,830
- Assignee:
- Genecor International, Inc. (Rochester, NY)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- W-31-198-ENG-38
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Donnelly, Mark, and Joachimiak, Andrzej. Methods for production of proteins in host cells. United States: N. p., 2004.
Web.
Donnelly, Mark, & Joachimiak, Andrzej. Methods for production of proteins in host cells. United States.
Donnelly, Mark, and Joachimiak, Andrzej. Tue .
"Methods for production of proteins in host cells". United States. https://www.osti.gov/servlets/purl/1174681.
@article{osti_1174681,
title = {Methods for production of proteins in host cells},
author = {Donnelly, Mark and Joachimiak, Andrzej},
abstractNote = {The present invention provides methods for the production of proteins, particularly toxic proteins, in host cells. The invention provides methods which use a fusion protein comprising a chaperonin binding domain in host cells induced or regulated to have increased levels of chaperonin which binds the chaperonin binding domain.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {1}
}
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