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Title: Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis

Abstract

A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction analysis, is disclosed. Preferably, fractions are collected in a multi-well fraction collection unit, or plate (40). The multi-well collection plate (40) is preferably made of a solvent permeable gel, most preferably a hydrophilic, polymeric gel such as agarose or cross-linked polyacrylamide.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Beckman Coulter, Inc., Fullerton, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174610
Patent Number(s):
6,660,149
Application Number:
09/530,118
Assignee:
Beckman Coulter, Inc. (Fullerton, CA) OSTI
DOE Contract Number:  
FG02-90ER60985
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Karger, Barry L., Kotler, Lev, Foret, Frantisek, Minarik, Marek, and Kleparnik, Karel. Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis. United States: N. p., 2003. Web.
Karger, Barry L., Kotler, Lev, Foret, Frantisek, Minarik, Marek, & Kleparnik, Karel. Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis. United States.
Karger, Barry L., Kotler, Lev, Foret, Frantisek, Minarik, Marek, and Kleparnik, Karel. Tue . "Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis". United States. https://www.osti.gov/servlets/purl/1174610.
@article{osti_1174610,
title = {Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis},
author = {Karger, Barry L. and Kotler, Lev and Foret, Frantisek and Minarik, Marek and Kleparnik, Karel},
abstractNote = {A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction analysis, is disclosed. Preferably, fractions are collected in a multi-well fraction collection unit, or plate (40). The multi-well collection plate (40) is preferably made of a solvent permeable gel, most preferably a hydrophilic, polymeric gel such as agarose or cross-linked polyacrylamide.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {12}
}

Patent:

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