Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis
Abstract
A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction analysis, is disclosed. Preferably, fractions are collected in a multi-well fraction collection unit, or plate (40). The multi-well collection plate (40) is preferably made of a solvent permeable gel, most preferably a hydrophilic, polymeric gel such as agarose or cross-linked polyacrylamide.
- Inventors:
- Issue Date:
- Research Org.:
- Beckman Coulter, Inc., Fullerton, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174610
- Patent Number(s):
- 6660149
- Application Number:
- 09/530,118
- Assignee:
- Beckman Coulter, Inc. (Fullerton, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG02-90ER60985
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Karger, Barry L., Kotler, Lev, Foret, Frantisek, Minarik, Marek, and Kleparnik, Karel. Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis. United States: N. p., 2003.
Web.
Karger, Barry L., Kotler, Lev, Foret, Frantisek, Minarik, Marek, & Kleparnik, Karel. Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis. United States.
Karger, Barry L., Kotler, Lev, Foret, Frantisek, Minarik, Marek, and Kleparnik, Karel. Tue .
"Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis". United States. https://www.osti.gov/servlets/purl/1174610.
@article{osti_1174610,
title = {Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis},
author = {Karger, Barry L. and Kotler, Lev and Foret, Frantisek and Minarik, Marek and Kleparnik, Karel},
abstractNote = {A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction analysis, is disclosed. Preferably, fractions are collected in a multi-well fraction collection unit, or plate (40). The multi-well collection plate (40) is preferably made of a solvent permeable gel, most preferably a hydrophilic, polymeric gel such as agarose or cross-linked polyacrylamide.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {12}
}
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