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Title: Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display

Abstract

The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

Inventors:
;
Issue Date:
Research Org.:
The Regents of the University of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174586
Patent Number(s):
6,649,376
Application Number:
09/469,194
Assignee:
The Regents of the University of California (Oakland, CA) OSTI
DOE Contract Number:  
FG-91ER61125
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Glazer, Alexander N., and Cai, Yuping. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display. United States: N. p., 2003. Web.
Glazer, Alexander N., & Cai, Yuping. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display. United States.
Glazer, Alexander N., and Cai, Yuping. Tue . "Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display". United States. https://www.osti.gov/servlets/purl/1174586.
@article{osti_1174586,
title = {Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display},
author = {Glazer, Alexander N. and Cai, Yuping},
abstractNote = {The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {11}
}

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