skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer

Abstract

A method for improving the calibration of a Fourier transform ion cyclotron resonance mass spectrometer wherein the frequency spectrum of a sample has been measured and the frequency (f) and intensity (I) of at least three species having known mass to charge (m/z) ratios and one specie having an unknown (m/z) ratio have been identified. The method uses the known (m/z) ratios, frequencies, and intensities at least three species to calculate coefficients A, B, and C, wherein the mass to charge ratio of a least one of the three species (m/z).sub.i is equal to ##EQU1## wherein f.sub.i is the detected frequency of the specie, G(I.sub.i) is a predetermined function of the intensity of the species, and Q is a predetermined exponent. Using the calculated values for A, B, and C, the mass to charge ratio of the unknown specie (m/z).sub.ii is calculated as the sum of ##EQU2## wherein f.sub.ii is the measured frequency of the unknown specie, and (I.sub.ii) is the measured intensity of the unknown specie.

Inventors:
; ;
Issue Date:
Research Org.:
~Individually Owned Patent
Sponsoring Org.:
USDOE
OSTI Identifier:
1174454
Patent Number(s):
6608302
Application Number:
09/870,577
Assignee:
Smith, Richard D.; Masselon, Christophe D.; Tolmachev, Aleksey
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Smith, Richard D., Masselon, Christophe D., and Tolmachev, Aleksey. Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer. United States: N. p., 2003. Web.
Smith, Richard D., Masselon, Christophe D., & Tolmachev, Aleksey. Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer. United States.
Smith, Richard D., Masselon, Christophe D., and Tolmachev, Aleksey. Tue . "Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer". United States. https://www.osti.gov/servlets/purl/1174454.
@article{osti_1174454,
title = {Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer},
author = {Smith, Richard D. and Masselon, Christophe D. and Tolmachev, Aleksey},
abstractNote = {A method for improving the calibration of a Fourier transform ion cyclotron resonance mass spectrometer wherein the frequency spectrum of a sample has been measured and the frequency (f) and intensity (I) of at least three species having known mass to charge (m/z) ratios and one specie having an unknown (m/z) ratio have been identified. The method uses the known (m/z) ratios, frequencies, and intensities at least three species to calculate coefficients A, B, and C, wherein the mass to charge ratio of a least one of the three species (m/z).sub.i is equal to ##EQU1## wherein f.sub.i is the detected frequency of the specie, G(I.sub.i) is a predetermined function of the intensity of the species, and Q is a predetermined exponent. Using the calculated values for A, B, and C, the mass to charge ratio of the unknown specie (m/z).sub.ii is calculated as the sum of ##EQU2## wherein f.sub.ii is the measured frequency of the unknown specie, and (I.sub.ii) is the measured intensity of the unknown specie.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {8}
}

Patent:

Save / Share: