Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer
Abstract
A method for improving the calibration of a Fourier transform ion cyclotron resonance mass spectrometer wherein the frequency spectrum of a sample has been measured and the frequency (f) and intensity (I) of at least three species having known mass to charge (m/z) ratios and one specie having an unknown (m/z) ratio have been identified. The method uses the known (m/z) ratios, frequencies, and intensities at least three species to calculate coefficients A, B, and C, wherein the mass to charge ratio of a least one of the three species (m/z).sub.i is equal to ##EQU1## wherein f.sub.i is the detected frequency of the specie, G(I.sub.i) is a predetermined function of the intensity of the species, and Q is a predetermined exponent. Using the calculated values for A, B, and C, the mass to charge ratio of the unknown specie (m/z).sub.ii is calculated as the sum of ##EQU2## wherein f.sub.ii is the measured frequency of the unknown specie, and (I.sub.ii) is the measured intensity of the unknown specie.
 Inventors:
 Issue Date:
 Research Org.:
 ~Individually Owned Patent
 Sponsoring Org.:
 USDOE
 OSTI Identifier:
 1174454
 Patent Number(s):
 6608302
 Application Number:
 09/870,577
 Assignee:
 Smith, Richard D.; Masselon, Christophe D.; Tolmachev, Aleksey
 Patent Classifications (CPCs):

H  ELECTRICITY H01  BASIC ELECTRIC ELEMENTS H01J  ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
 DOE Contract Number:
 AC0676RL01830
 Resource Type:
 Patent
 Country of Publication:
 United States
 Language:
 English
 Subject:
 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Smith, Richard D., Masselon, Christophe D., and Tolmachev, Aleksey. Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer. United States: N. p., 2003.
Web.
Smith, Richard D., Masselon, Christophe D., & Tolmachev, Aleksey. Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer. United States.
Smith, Richard D., Masselon, Christophe D., and Tolmachev, Aleksey. Tue .
"Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer". United States. https://www.osti.gov/servlets/purl/1174454.
@article{osti_1174454,
title = {Method for calibrating a Fourier transform ion cyclotron resonance mass spectrometer},
author = {Smith, Richard D. and Masselon, Christophe D. and Tolmachev, Aleksey},
abstractNote = {A method for improving the calibration of a Fourier transform ion cyclotron resonance mass spectrometer wherein the frequency spectrum of a sample has been measured and the frequency (f) and intensity (I) of at least three species having known mass to charge (m/z) ratios and one specie having an unknown (m/z) ratio have been identified. The method uses the known (m/z) ratios, frequencies, and intensities at least three species to calculate coefficients A, B, and C, wherein the mass to charge ratio of a least one of the three species (m/z).sub.i is equal to ##EQU1## wherein f.sub.i is the detected frequency of the specie, G(I.sub.i) is a predetermined function of the intensity of the species, and Q is a predetermined exponent. Using the calculated values for A, B, and C, the mass to charge ratio of the unknown specie (m/z).sub.ii is calculated as the sum of ##EQU2## wherein f.sub.ii is the measured frequency of the unknown specie, and (I.sub.ii) is the measured intensity of the unknown specie.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {8}
}