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Title: Sample preparation and detection device for infectious agents

Abstract

A sample preparation and analysis device which incorporates both immunoassays and PCR assays in one compact, field-portable microchip. The device provides new capabilities in fluid and particle control which allows the building of a fluidic chip with no moving parts, thus decreasing fabrication cost and increasing the robustness of the device. The device can operate in a true continuous (not batch) mode. The device incorporates magnetohydrodynamic (MHD) pumps to move the fluid through the system, acoustic mixing and fractionation, dielectropheretic (DEP) sample concentration and purification, and on-chip optical detection capabilities.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174366
Patent Number(s):
6576459
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Miles, Robin R., Wang, Amy W., Fuller, Christopher K., Lemoff, Asuncion V., Bettencourt, Kerry A., and Yu, June. Sample preparation and detection device for infectious agents. United States: N. p., 2003. Web.
Miles, Robin R., Wang, Amy W., Fuller, Christopher K., Lemoff, Asuncion V., Bettencourt, Kerry A., & Yu, June. Sample preparation and detection device for infectious agents. United States.
Miles, Robin R., Wang, Amy W., Fuller, Christopher K., Lemoff, Asuncion V., Bettencourt, Kerry A., and Yu, June. Tue . "Sample preparation and detection device for infectious agents". United States. https://www.osti.gov/servlets/purl/1174366.
@article{osti_1174366,
title = {Sample preparation and detection device for infectious agents},
author = {Miles, Robin R. and Wang, Amy W. and Fuller, Christopher K. and Lemoff, Asuncion V. and Bettencourt, Kerry A. and Yu, June},
abstractNote = {A sample preparation and analysis device which incorporates both immunoassays and PCR assays in one compact, field-portable microchip. The device provides new capabilities in fluid and particle control which allows the building of a fluidic chip with no moving parts, thus decreasing fabrication cost and increasing the robustness of the device. The device can operate in a true continuous (not batch) mode. The device incorporates magnetohydrodynamic (MHD) pumps to move the fluid through the system, acoustic mixing and fractionation, dielectropheretic (DEP) sample concentration and purification, and on-chip optical detection capabilities.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {6}
}