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Title: Microbial production of epoxides

Abstract

A method for microbial production of epoxides and other oxygenated products is disclosed. The method uses a biocatalyst of methanotrophic bacteria cultured in a biphasic medium containing a major amount of a non-aqueous polar solvent. Regeneration of reducing equivalents is carried out by using endogenous hydrogenase activity together with supplied hydrogen gas. This method is especially effective with gaseous substrates and cofactors that result in liquid products.

Inventors:
;
Issue Date:
Research Org.:
Idaho National Lab. (INL), Idaho Falls, ID (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174365
Patent Number(s):
6,576,449
Application Number:
09/805,795
Assignee:
Bechtel BWXT Idaho, LLC (Idaho Falls, ID) OSTI
DOE Contract Number:  
AC07-94ID13223
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Clark, Thomas R., and Roberto, Francisco F. Microbial production of epoxides. United States: N. p., 2003. Web.
Clark, Thomas R., & Roberto, Francisco F. Microbial production of epoxides. United States.
Clark, Thomas R., and Roberto, Francisco F. Tue . "Microbial production of epoxides". United States. https://www.osti.gov/servlets/purl/1174365.
@article{osti_1174365,
title = {Microbial production of epoxides},
author = {Clark, Thomas R. and Roberto, Francisco F.},
abstractNote = {A method for microbial production of epoxides and other oxygenated products is disclosed. The method uses a biocatalyst of methanotrophic bacteria cultured in a biphasic medium containing a major amount of a non-aqueous polar solvent. Regeneration of reducing equivalents is carried out by using endogenous hydrogenase activity together with supplied hydrogen gas. This method is especially effective with gaseous substrates and cofactors that result in liquid products.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {6}
}

Patent:

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