Formulations for neutralization of chemical and biological toxants
Abstract
A formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents. The formulation of the present invention non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The at least one reactive compound can be an oxidizing compound, a nucleophilic compound or a mixture of both. The formulation can kill up to 99.99999% of bacterial spores within one hour of exposure.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-CA), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174337
- Patent Number(s):
- 6566574
- Application Number:
- 09/607,586
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A62 - LIFE-SAVING A62D - CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Tadros, Maher E., and Tucker, Mark D. Formulations for neutralization of chemical and biological toxants. United States: N. p., 2003.
Web.
Tadros, Maher E., & Tucker, Mark D. Formulations for neutralization of chemical and biological toxants. United States.
Tadros, Maher E., and Tucker, Mark D. Tue .
"Formulations for neutralization of chemical and biological toxants". United States. https://www.osti.gov/servlets/purl/1174337.
@article{osti_1174337,
title = {Formulations for neutralization of chemical and biological toxants},
author = {Tadros, Maher E. and Tucker, Mark D.},
abstractNote = {A formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents. The formulation of the present invention non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The at least one reactive compound can be an oxidizing compound, a nucleophilic compound or a mixture of both. The formulation can kill up to 99.99999% of bacterial spores within one hour of exposure.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {5}
}
Works referenced in this record:
Comparative sporicidal effects of liquid chemical agents.
journal, January 1996
- Sagripanti, J. L.; Bonifacino, A.
- Applied and environmental microbiology, Vol. 62, Issue 2
Efficient catalytic cleavage of reactive phosphates by a functionalized o-iodosobenzoate surfactant
journal, February 1986
- Moss, Robert A.; Kim, Kwang Yoo.; Swarup, Shanti.
- Journal of the American Chemical Society, Vol. 108, Issue 4
Peroxyhydrolysis of nerve agent VX and model compounds and related nucleophilic reactions
journal, January 1997
- Yang, Yu-Chu; Berg, Frederic J.; Szafraniec, Linda L.
- Journal of the Chemical Society, Perkin Transactions 2, Issue 3
Synthesis of hybrid inorganic–organic mesoporous silica by co-condensation of siloxane and organosiloxane precursors
journal, January 1996
- Burkett, Sandra L.; Sims, Stephen D.; Mann, Stephen
- Chem. Commun., Issue 11
Lysis of Bacterial Spores with Hydrogen Peroxide
journal, December 1969
- King, W. L.; Gould, G. W.
- Journal of Applied Bacteriology, Vol. 32, Issue 4
Toward a broad spectrum decontaminant for reactive toxic phosphates/phosphonates: N-alkyl-3-iodosopyridinium-4-carboxylates
journal, September 1993
- Moss, Robert A.; Zhang, Hongmei
- Tetrahedron Letters, Vol. 34, Issue 39
Bacterial spores and chemical sporicidal agents.
journal, April 1990
- Russell, A. D.
- Clinical Microbiology Reviews, Vol. 3, Issue 2
Structure and Composition of Resistant Layers in Bacterial Spore Coats
journal, March 1970
- Gould, G. W.; Stubbs, J. M.; King, W. L.
- Journal of General Microbiology, Vol. 60, Issue 3