skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy

Abstract

The present invention covers halogenated derivatives of boronated porphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron- capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.

Inventors:
;
Issue Date:
Research Org.:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1174335
Patent Number(s):
6,566,517
Application Number:
09/874,203
Assignee:
Brookhaven Science Associates, LLC (Upton, NY) BNL
DOE Contract Number:  
AC02-98CH10886
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY

Citation Formats

Miura, Michiko, and Slatkin, Daniel N. Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy. United States: N. p., 2003. Web.
Miura, Michiko, & Slatkin, Daniel N. Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy. United States.
Miura, Michiko, and Slatkin, Daniel N. Tue . "Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy". United States. https://www.osti.gov/servlets/purl/1174335.
@article{osti_1174335,
title = {Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy},
author = {Miura, Michiko and Slatkin, Daniel N.},
abstractNote = {The present invention covers halogenated derivatives of boronated porphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron- capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {5}
}

Patent:

Save / Share: