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Title: Increasing cell culture population doublings for long-term growth of finite life span human cell cultures

Cell culture media formulations for culturing human epithelial cells are herein described. Also described are methods of increasing population doublings in a cell culture of finite life span human epithelial cells and prolonging the life span of human cell cultures. Using the cell culture media disclosed alone and in combination with addition to the cell culture of a compound associated with anti-stress activity achieves extended growth of pre-stasis cells and increased population doublings and life span in human epithelial cell cultures.
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OSTI Identifier:
The Regents of the University of California (Oakland, CA) CHO
Patent Number(s):
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Resource Relation:
Patent File Date: 2008 Sep 30
Research Org:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org:
Country of Publication:
United States

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