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Title: Methods for isolation and viability assessment of biological organisms

Abstract

Isolation of biological or chemical organisms can be accomplished using a surface enhanced Raman scattering (SERS) system. The SERS system can be a single or a stacked plurality of photonic crystal membranes with noble-metal lined through pores for flowing analyte potentially containing the biological or chemical organisms. The through pores can be adapted to trap individual biological or chemical organisms and emit SERS spectra, which can then be detected by a detector and further analyzed for viability of the biological or chemical organism.

Inventors:
; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1169062
Patent Number(s):
8,947,657
Application Number:
13/117,079
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Letant, Sonia Edith, Baker, Sarah Elyse, Bond, Tiziana, and Chang, Allan Shih-Ping. Methods for isolation and viability assessment of biological organisms. United States: N. p., 2015. Web.
Letant, Sonia Edith, Baker, Sarah Elyse, Bond, Tiziana, & Chang, Allan Shih-Ping. Methods for isolation and viability assessment of biological organisms. United States.
Letant, Sonia Edith, Baker, Sarah Elyse, Bond, Tiziana, and Chang, Allan Shih-Ping. Tue . "Methods for isolation and viability assessment of biological organisms". United States. https://www.osti.gov/servlets/purl/1169062.
@article{osti_1169062,
title = {Methods for isolation and viability assessment of biological organisms},
author = {Letant, Sonia Edith and Baker, Sarah Elyse and Bond, Tiziana and Chang, Allan Shih-Ping},
abstractNote = {Isolation of biological or chemical organisms can be accomplished using a surface enhanced Raman scattering (SERS) system. The SERS system can be a single or a stacked plurality of photonic crystal membranes with noble-metal lined through pores for flowing analyte potentially containing the biological or chemical organisms. The through pores can be adapted to trap individual biological or chemical organisms and emit SERS spectra, which can then be detected by a detector and further analyzed for viability of the biological or chemical organism.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {2}
}

Patent:

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journal, November 2005

  • Rindzevicius, Tomas; Alaverdyan, Yury; Dahlin, Andreas
  • Nano Letters, Vol. 5, Issue 11
  • DOI: 10.1021/nl0516355

Internal Electric Field Densities of Metal Nanoshells
journal, February 2005

  • Schelm, Stefan; Smith, Geoff B.
  • The Journal of Physical Chemistry B, Vol. 109, Issue 5
  • DOI: 10.1021/jp0450686

Localized Surface Plasmon Resonance Spectroscopy of Single Silver Triangular Nanoprisms
journal, September 2006

  • Sherry, Leif J.; Jin, Rongchao; Mirkin, Chad A.
  • Nano Letters, Vol. 6, Issue 9
  • DOI: 10.1021/nl061286u

Optical characterization of electronic transitions arising from the Au/S interface of self-assembled n-alkanethiolate monolayers
journal, November 1995


Fabrication of Crescent-Shaped Optical Antennas
journal, September 2005

  • Shumaker-Parry, J. S.; Rochholz, H.; Kreiter, M.
  • Advanced Materials, Vol. 17, Issue 17, p. 2131-2134
  • DOI: 10.1002/adma.200500063

Spectroscopy of single metallic nanoparticles using total internal reflection microscopy
journal, November 2000

  • Sönnichsen, C.; Geier, S.; Hecker, N. E.
  • Applied Physics Letters, Vol. 77, Issue 19
  • DOI: 10.1063/1.1323553

Optical Antenna Arrays on a Fiber Facet for in Situ Surface-Enhanced Raman Scattering Detection
journal, March 2009

  • Smythe, Elizabeth J.; Dickey, Michael D.; Bao, Jiming
  • Nano Letters, Vol. 9, Issue 3
  • DOI: 10.1021/nl803668u

Geometrical Parameters Controlling Sensitivity of Nanoshell Plasmon Resonances to Changes in Dielectric Environment
journal, November 2004

  • Tam, Felicia; Moran, Cristin; Halas, Naomi
  • The Journal of Physical Chemistry B, Vol. 108, Issue 45
  • DOI: 10.1021/jp048499x

Langmuir−Blodgett Silver Nanowire Monolayers for Molecular Sensing Using Surface-Enhanced Raman Spectroscopy
journal, September 2003

  • Tao, Andrea; Kim, Franklin; Hess, Christian
  • Nano Letters, Vol. 3, Issue 9, p. 1229-1233
  • DOI: 10.1021/nl0344209

Single-fibre surface-enhanced Raman sensors with angled tips
journal, January 2000


Comparison of fibre-optic SERS sensors with differently prepared tips
journal, August 1998


Nanorice:  A Hybrid Plasmonic Nanostructure
journal, April 2006

  • Wang, Hui; Brandl, Daniel W.; Le, Fei
  • Nano Letters, Vol. 6, Issue 4
  • DOI: 10.1021/nl060209w

Highly Sensitive Detection of Proteins and Bacteria in Aqueous Solution Using Surface-Enhanced Raman Scattering and Optical Fibers
journal, August 2011

  • Yang, Xuan; Gu, Claire; Qian, Fang
  • Analytical Chemistry, Vol. 83, Issue 15
  • DOI: 10.1021/ac200707t

High-sensitivity molecular sensing using hollow-core photonic crystal fiber and surface-enhanced Raman scattering
journal, January 2010

  • Yang, Xuan; Shi, Chao; Wheeler, Damon
  • Journal of the Optical Society of America A, Vol. 27, Issue 5
  • DOI: 10.1364/JOSAA.27.000977

Portable fiber sensors based on surface-enhanced Raman scattering
journal, December 2010

  • Yang, Xuan; Tanaka, Zuki; Newhouse, Rebecca
  • Review of Scientific Instruments, Vol. 81, Issue 12
  • DOI: 10.1063/1.3518957

Nanopillar array on a fiber facet for highly sensitive surface-enhanced Raman scattering
journal, January 2012

  • Yang, Xuan; Ileri, Nazar; Larson, Cindy C.
  • Optics Express, Vol. 20, Issue 22
  • DOI: 10.1364/OE.20.024819

A Comparative Analysis of Localized and Propagating Surface Plasmon Resonance Sensors:  The Binding of Concanavalin A to a Monosaccharide Functionalized Self-Assembled Monolayer
journal, October 2004

  • Yonzon, Chanda Ranjit; Jeoung, Eunhee; Zou, Shengli
  • Journal of the American Chemical Society, Vol. 126, Issue 39
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Development of silver nanorod array based fiber optic probes for SERS detection
journal, September 2011

  • Zhu, Yu; Dluhy, Richard A.; Zhao, Yiping
  • Sensors and Actuators B: Chemical, Vol. 157, Issue 1, p. 42-50
  • DOI: 10.1016/j.snb.2011.03.024

Rapidly reconfigurable all-optical universal logic gates
conference, October 2006

  • Goddard, Lynford L.; Kallman, Jeffrey S.; Bond, Tiziana C.
  • Optics East 2006
  • DOI: 10.1117/12.686169

Sampled-grating DBR laser-based analog optical transmitters
journal, December 2003

  • Johansson, L. A.; Getty, J. T.; Akulova, Y. A.
  • Journal of Lightwave Technology, Vol. 21, Issue 12
  • DOI: 10.1109/JLT.2003.819786

Gain lever characterization in monolithically integrated diode lasers
conference, April 2005

  • Pocha, Michael; Bond, Tiziana; Welty, Rebecca
  • Integrated Optoelectronic Devices 2005
  • DOI: 10.1117/12.590904

Integrated laser with low-loss high-index-contrast waveguides for OEICs
conference, March 2005

  • Welty, Rebecca J.; Bond, Tiziana C.; Behymer, Elaine
  • Integrated Optoelectronic Devices 2005
  • DOI: 10.1117/12.591182

Rapid and Sensitive Detection of Respiratory Virus Molecular Signatures Using a Silver Nanorod Array SERS Substrate
journal, November 2006

  • Shanmukh, Saratchandra; Jones, Les; Driskell, Jeremy
  • Nano Letters, Vol. 6, Issue 11
  • DOI: 10.1021/nl061666f