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Title: Fibrous microcapsules and methods of assembly and use thereof

The present invention relates to assembly of peptide amphiphiles and biopolymers into fibrous microcapsules, and uses thereof. In particular, the present invention provides devices, compositions, and methods for interfacial self-assembly of peptide amphiphiles and biopolyments into fibrous microcapsules, and uses thereof.
Inventors:
;
Issue Date:
OSTI Identifier:
1168683
Assignee:
Northwestern University (Evanston, IL) CHO
Patent Number(s):
8,940,858
Application Number:
13/109,186
Contract Number:
FG02-00ER45810
Research Org:
Northwestern Univ., Evanston, IL (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE

Other works cited in this record:

Building from the bottom up
journal, May 2003

Molecular self-assembly of surfactant-like peptides to form nanotubes and nanovesicles
journal, April 2002
  • Vauthey, S.; Santoso, S.; Gong, H.
  • Proceedings of the National Academy of Sciences, Vol. 99, Issue 8, p. 5355-5360
  • DOI: 10.1073/pnas.072089599

Self-Assembly of Large and Small Molecules into Hierarchically Ordered Sacs and Membranes
journal, March 2008
  • Capito, R. M.; Azevedo, H. S.; Velichko, Y. S.
  • Science, Vol. 319, Issue 5871, p. 1812-1816
  • DOI: 10.1126/science.1154586

Novel Hollow Polymer Shells by Colloid-Templated Assembly of Polyelectrolytes
journal, September 1998

Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials
journal, April 2002
  • Hartgerink, J. D.; Beniash, E.; Stupp, S. I.
  • Proceedings of the National Academy of Sciences, Vol. 99, Issue 8, p. 5133-5138
  • DOI: 10.1073/pnas.072699999

Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials
journal, April 2002
  • Hartgerink, J. D.; Beniash, E.; Stupp, S. I.
  • Proceedings of the National Academy of Sciences, Vol. 99, Issue 8, p. 5133-5138
  • DOI: 10.1073/pnas.072699999

Charged droplet formation in sonic spray
journal, May 1998
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  • DOI: 10.1016/S0168-1176(98)00129-3

Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
journal, February 2004
  • Silva, Gabriel A.; Czeisler, Catherine; Niece, Krista L.
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  • DOI: 10.1126/science.1093783

Encapsulation and sustained release from biodegradable microcapsules made by emulsification/freeze drying and spray/freeze drying
journal, August 2009
  • Yin, Weisi; Yates, M. Z.
  • Journal of Colloid and Interface Science, Vol. 336, Issue 1, p. 155-161
  • DOI: 10.1016/j.jcis.2009.03.065

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