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Title: Method for non-contact particle manipulation and control of particle spacing along an axis

Method and system for uniformly spacing particles in a flowing system comprising suspending particles in an elongated fluid filled cavity; exposing said cavity to an axial acoustic standing wave field, wherein said axial acoustic standing wave field drives said particles to nodal and anti-nodal positions along the center axis of said cavity to result in uniformly spaced particles; and focusing said particles to the center axis of said cavity.
Inventors:
; ; ;
Issue Date:
OSTI Identifier:
1167220
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM) LANL
Patent Number(s):
8,932,520
Application Number:
13/570,605
Contract Number:
AC52-06NA25396
Resource Relation:
Patent File Date: 2012 Aug 09
Research Org:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS

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Particle column formation in a stationary ultrasonic field
journal, January 1992
  • Whitworth, Glenn; Coakley, W. T.
  • The Journal of the Acoustical Society of America, Vol. 91, Issue 1, p. 79-85
  • DOI: 10.1121/1.402622

Transport and harvesting of suspended particles using modulated ultrasound
journal, November 1991

Diazo Coupling Method for Covalent Attachment of Proteins to Solid Substrates
journal, March 2006
  • Wu, Yang; Buranda, Tione; Metzenberg, Robert L.
  • Bioconjugate Chemistry, Vol. 17, Issue 2, p. 359-365
  • DOI: 10.1021/bc050278m

Flow cytometry to evaluate Theileria sergenti parasitemia using the fluorescent nucleic acid stain, SYTO16
journal, January 2000

Micro particle trapping by opposite phases ultrasonic travelling waves
journal, July 1998

Deoxyribonucleic acid concentration using acoustic radiation force
journal, February 1996
  • Yasuda, Kenji; Kiyama, Masaharu; Umemura, Shin‐ichiro
  • The Journal of the Acoustical Society of America, Vol. 99, Issue 2, p. 1248-1251
  • DOI: 10.1121/1.414635

Non-destructive, non-contact handling method for biomaterials in micro-chamber by ultrasound
journal, June 2000

Particle separation using acoustic radiation force and elecrostatic force
journal, April 1996
  • Yasuda, Kenji; Umemura, Shin‐ichiro; Takeda, Kazuo
  • The Journal of the Acoustical Society of America, Vol. 99, Issue 4, p. 1965-1970
  • DOI: 10.1121/1.415382

Lanthanide-based luminescence probes and time-resolved luminescence bioassays
journal, May 2006

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