Global to push GA events into
skip to main content

Title: Semiconductor nanocrystal-based phagokinetic tracking

Methods for determining metabolic properties of living cells through the uptake of semiconductor nanocrystals by cells. Generally the methods require a layer of neutral or hydrophilic semiconductor nanocrystals and a layer of cells seeded onto a culture surface and changes in the layer of semiconductor nanocrystals are detected. The observed changes made to the layer of semiconductor nanocrystals can be correlated to such metabolic properties as metastatic potential, cell motility or migration.
; ; ; ;
Issue Date:
OSTI Identifier:
The Regents of the University of California (Oakland, CA) OAK
Patent Number(s):
Application Number:
Contract Number:
Research Org:
Oakland Operations Office, Oakland, CA (United States)
Sponsoring Org:
Country of Publication:
United States

Works referenced in this record:

Scanning electrochemical microscopy of living cells: Different redox activities of nonmetastatic and metastatic human breast cells
journal, August 2000
  • Liu, B.; Rotenberg, S. A.; Mirkin, M. V.
  • Proceedings of the National Academy of Sciences, Vol. 97, Issue 18, p. 9855-9860
  • DOI: 10.1073/pnas.97.18.9855

Measurement of cell migration stimulated by interleukin 8: Use of ATP chemiluminescence
journal, July 1994

A sensitive screening assay for secreted motility-stimulating factors
journal, January 2000

An indirect bioluminescence method for the quantitative measurement of polymorphonuclear cell chemotaxis
journal, July 1991
  • Partsch, Gerald; Schwarzer, Christine
  • Luminescence: The Journal of Biological and Chemical Luminescence, Vol. 6, Issue 3, p. 159-167
  • DOI: 10.1002/bio.1170060305

Comparison of MTT and ATP-based assays for the measurement of viable cell number
journal, January 1995
  • Petty, Russell D.; Sutherland, Lesley A.; Hunter, Elizabeth M.
  • Luminescence: The Journal of Biological and Chemical Luminescence, Vol. 10, Issue 1, p. 29-34
  • DOI: 10.1002/bio.1170100105

Development of a novel human extracellular matrix for quantitation of the invasiveness of human cells
journal, April 1993

The influence of ethanol on cell membrane fluidity, migration, and invasion of murine melanoma cells
journal, July 1990
  • Silberman, Simone; McGarvey, Terence W.; Comrie, Eric
  • Experimental Cell Research, Vol. 189, Issue 1, p. 64-68
  • DOI: 10.1016/0014-4827(90)90257-B

The promotion of invasion through the basement membrane of cervical carcinoma cells by fibronectin as a chemoattractant
journal, May 1994

The phagokinetic tracks of 3T3 cells
journal, June 1977

Proliferative and migratory responses of astrocytes to in vitro injury
journal, January 2000

Semiconductor Nanocrystals as Fluorescent Biological Labels
patent, September 1998

Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
journal, September 1998

Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules
journal, July 2001
  • Han, Mingyong; Gao, Xiaohu; Su, Jack Z.
  • Nature Biotechnology, Vol. 19, Issue 7, p. 631-635
  • DOI: 10.1038/90228

Shape control of CdSe nanocrystals
journal, March 2000
  • Peng, Xiaogang; Manna, Liberato; Yang, Weidong
  • Nature, Vol. 404, Issue 6773, p. 59-61
  • DOI: 10.1038/35003535