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Title: Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits

Abstract

Methods to synthesize self-assembling peptides embedded with complex organic electronic subunits are provided.

Inventors:
;
Issue Date:
Research Org.:
The Johns Hopkins University, Baltimore, MD (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1162112
Patent Number(s):
8,871,903
Application Number:
13/657,219
Assignee:
The Johns Hopkins University (Baltimore, MD)
DOE Contract Number:  
SC0004857
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Oct 22
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Tovar, John D, and Sanders, Allix M. Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits. United States: N. p., 2014. Web.
Tovar, John D, & Sanders, Allix M. Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits. United States.
Tovar, John D, and Sanders, Allix M. Tue . "Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits". United States. https://www.osti.gov/servlets/purl/1162112.
@article{osti_1162112,
title = {Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits},
author = {Tovar, John D and Sanders, Allix M},
abstractNote = {Methods to synthesize self-assembling peptides embedded with complex organic electronic subunits are provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {10}
}

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Works referenced in this record:

Exploiting Site−Site Interactions on Solid Support to Generate Dimeric Molecules
journal, April 2001

  • Blackwell, Helen E.; Clemons, Paul A.; Schreiber, Stuart L.
  • Organic Letters, Vol. 3, Issue 8
  • DOI: 10.1021/ol015647i

Palladium-catalysed reactions in solid phase organic synthesis
journal, February 2003


Energy transfer in self-assembled dipeptide hydrogels
journal, January 2010

  • Chen, Lin; Revel, Steven; Morris, Kyle
  • Chemical Communications, Vol. 46, Issue 24
  • DOI: 10.1039/c003052j

Synthesis of symmetrical dimeric N,N′-linked peptides on solid support by olefin metathesis
journal, November 2000

  • Conde-Frieboes, Kilian; Andersen, Stina; Breinholt, Jens
  • Tetrahedron Letters, Vol. 41, Issue 47, p. 9153-9156
  • DOI: 10.1016/S0040-4039(00)01637-3

One-Dimensional Optoelectronic Nanostructures Derived from the Aqueous Self-Assembly of π-Conjugated Oligopeptides
journal, October 2008

  • Diegelmann, Stephen R.; Gorham, Justin M.; Tovar, John D.
  • Journal of the American Chemical Society, Vol. 130, Issue 42
  • DOI: 10.1021/ja805491d

Effectiveness of the Suzuki−Miyaura Cross-Coupling Reaction for Solid-Phase Peptide Modification
journal, January 2008

  • Doan, Ngoc-Duc; Bourgault, Steve; Létourneau, Myriam
  • Journal of Combinatorial Chemistry, Vol. 10, Issue 1
  • DOI: 10.1021/cc700128b

Conjugated Polymers from Naphthalene Bisimide
journal, December 2008

  • Guo, Xugang; Watson, Mark D.
  • Organic Letters, Vol. 10, Issue 23, p. 5333-5336
  • DOI: 10.1021/ol801918y

Synthesis and Photovoltaic Properties of Two-Dimensional Conjugated Polythiophenes with Bi(thienylenevinylene) Side Chains
journal, April 2006

  • Hou, Jianhui; Tan, Zhan'ao; Yan, Yong
  • Journal of the American Chemical Society, Vol. 128, Issue 14
  • DOI: 10.1021/ja060141m

Regulation of electronic behavior via confinement of PPV-based oligomers on peptide scaffolds
journal, January 2008

  • Kas, Onur Y.; Charati, Manoj B.; Rothberg, Lewis J.
  • Journal of Materials Chemistry, Vol. 18, Issue 32
  • DOI: 10.1039/b800860d

Chiral Aggregates of α,ω-Disubstituted Sexithiophenes in Protic and Aqueous Media
journal, March 2000

  • Kilbinger, A. F. M.; Schenning, A. P. H. J.; Goldoni, F.
  • Journal of the American Chemical Society, Vol. 122, Issue 8
  • DOI: 10.1021/ja994231l

Supramolecular Gel Based on a Perylene Diimide Dye: Multiple Stimuli Responsiveness, Robustness, and Photofunction
journal, October 2009

  • Krieg, Elisha; Shirman, Elijah; Weissman, Haim
  • Journal of the American Chemical Society, Vol. 131, Issue 40
  • DOI: 10.1021/ja903938g

Hierarchical Self-Assembly of Semiconductor Functionalized Peptide α-Helices and Optoelectronic Properties
journal, June 2011

  • Kumar, Rohan J.; MacDonald, James M.; Singh, Th. Birendra
  • Journal of the American Chemical Society, Vol. 133, Issue 22
  • DOI: 10.1021/ja110858k

Solid-Phase Synthesis of Smac Peptidomimetics Incorporating Triazoloprolines and Biarylalanines
journal, September 2011

  • Le Quement, Sebastian T.; Ishoey, Mette; Petersen, Mette T.
  • ACS Combinatorial Science, Vol. 13, Issue 6
  • DOI: 10.1021/co200078u

Convergent Solid-Phase Synthesis of Symmetrical Benzo[ b ]furan's Dimerizer
journal, March 2003

  • Liao, Yun; Fathi, Reza; Yang, Zhen
  • Journal of Combinatorial Chemistry, Vol. 5, Issue 2
  • DOI: 10.1021/cc020049w

Palladium-catalyzed reduction of alkynes employing HSiEt3: stereoselective synthesis of trans- and cis-alkenes
journal, February 2010


Parallel Synthesis of H-pin Polyamides by Alkene Metathesis on Solid Phase
journal, April 2003

  • Olenyuk, Bogdan; Jitianu, Cristian; Dervan, Peter B.
  • Journal of the American Chemical Society, Vol. 125, Issue 16
  • DOI: 10.1021/ja0213221

Oligothiophene Versus β-Sheet Peptide: Synthesis and Self-Assembly of an Organic Semiconductor-Peptide Hybrid
journal, April 2009

  • Schillinger, Eva-Kathrin; Mena-Osteritz, Elena; Hentschel, Jens
  • Advanced Materials, Vol. 21, Issue 16, p. 1562-1567
  • DOI: 10.1002/adma.200803110

A π-conjugated hydrogel based on an Fmoc-dipeptide naphthalene diimide semiconductor
journal, January 2010

  • Shao, Hui; Parquette, Jon R.
  • Chemical Communications, Vol. 46, Issue 24
  • DOI: 10.1039/C0CC00701C

Self-Assembling Nanofibers from Thiophene–Peptide Diblock Oligomers: A Combined Experimental and Computer Simulations Study
journal, August 2011

  • Shaytan, Alexey K.; Schillinger, Eva-Kathrin; Khalatur, Pavel G.
  • ACS Nano, Vol. 5, Issue 9
  • DOI: 10.1021/nn2011943

Fine-Tuned Nanostructures Assembled from l -Lysine-Functionalized Perylene Bisimides
journal, September 2011


Prospect of Metal-Catalyzed C−C Forming Cross-Coupling Reactions in Modern Solid-Phase Organic Synthesis
journal, July 2008

  • Testero, Sebastián A.; Mata, Ernesto G.
  • Journal of Combinatorial Chemistry, Vol. 10, Issue 4
  • DOI: 10.1021/cc800020b

Development of a robust supramolecular method to prepare well-defined nanofibrils from conjugated molecules
journal, January 2012

  • Tian, Liangfei; Szilluweit, Ruth; Marty, Roman
  • Chemical Science, Vol. 3, Issue 5
  • DOI: 10.1039/c2sc00977c

On-resin dimerization incorporates a diverse array of π-conjugated functionality within aqueous self-assembling peptide backbones
journal, January 2010

  • Vadehra, Geeta S.; Wall, Brian D.; Diegelmann, Stephen R.
  • Chemical Communications, Vol. 46, Issue 22
  • DOI: 10.1039/c0cc00301h

Aligned Macroscopic Domains of Optoelectronic Nanostructures Prepared via Shear-Flow Assembly of Peptide Hydrogels
journal, October 2011

  • Wall, Brian D.; Diegelmann, Stephen R.; Zhang, Shuming
  • Advanced Materials, Vol. 23, Issue 43, p. 5009-5014
  • DOI: 10.1002/adma.201102963