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Title: Microorganisms having enhanced resistance to acetate and methods of use

Abstract

The present invention provides isolated or genetically modified strains of microorganisms that display enhanced resistance to acetate as a result of increased expression of a sodium proton antiporter. The present invention also provides methods for producing such microbial strains, as well as related promoter sequences and expression vectors. Further, the present invention provides methods of producing alcohol from biomass materials by using microorganisms with enhanced resistance to acetate.

Inventors:
;
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1160260
Patent Number(s):
8865440
Application Number:
13/688,636
Assignee:
UT-Batelle, LLC (Oakridge, TN)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
ACO5-000R22725
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Nov 29
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Brown, Steven D, and Yang, Shihui. Microorganisms having enhanced resistance to acetate and methods of use. United States: N. p., 2014. Web.
Brown, Steven D, & Yang, Shihui. Microorganisms having enhanced resistance to acetate and methods of use. United States.
Brown, Steven D, and Yang, Shihui. Tue . "Microorganisms having enhanced resistance to acetate and methods of use". United States. https://www.osti.gov/servlets/purl/1160260.
@article{osti_1160260,
title = {Microorganisms having enhanced resistance to acetate and methods of use},
author = {Brown, Steven D and Yang, Shihui},
abstractNote = {The present invention provides isolated or genetically modified strains of microorganisms that display enhanced resistance to acetate as a result of increased expression of a sodium proton antiporter. The present invention also provides methods for producing such microbial strains, as well as related promoter sequences and expression vectors. Further, the present invention provides methods of producing alcohol from biomass materials by using microorganisms with enhanced resistance to acetate.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {10}
}

Patent:

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Works referenced in this record:

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