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Title: L-arabinose fermenting yeast

Abstract

An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1159899
Patent Number(s):
8841090
Application Number:
13/744,023
Assignee:
Alliance for Sustainable Energy, LLC (Golden, CO)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
AC36-99GO10337
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
09 BIOMASS FUELS; 60 APPLIED LIFE SCIENCES

Citation Formats

Zhang, Min, Singh, Arjun, Suominen, Pirkko, Knoshaug, Eric, Franden, Mary Ann, and Jarvis, Eric. L-arabinose fermenting yeast. United States: N. p., 2014. Web.
Zhang, Min, Singh, Arjun, Suominen, Pirkko, Knoshaug, Eric, Franden, Mary Ann, & Jarvis, Eric. L-arabinose fermenting yeast. United States.
Zhang, Min, Singh, Arjun, Suominen, Pirkko, Knoshaug, Eric, Franden, Mary Ann, and Jarvis, Eric. Tue . "L-arabinose fermenting yeast". United States. https://www.osti.gov/servlets/purl/1159899.
@article{osti_1159899,
title = {L-arabinose fermenting yeast},
author = {Zhang, Min and Singh, Arjun and Suominen, Pirkko and Knoshaug, Eric and Franden, Mary Ann and Jarvis, Eric},
abstractNote = {An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {9}
}

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